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1. (WO2018057847) UNSTRUCTURED NON-REPETITIVE POLYPEPTIDES HAVING LCST BEHAVIOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/057847 International Application No.: PCT/US2017/052887
Publication Date: 29.03.2018 International Filing Date: 22.09.2017
IPC:
C07K 14/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Applicants: DUKE UNIVERSITY[US/US]; 2812 Erwin Road Suite 306 Durham, NC 27705, US
Inventors: CHILKOTI, Ashutosh; US
TANG, Nicholas; US
KELLY, Garrett; US
Agent: ZERN, Blaine, J.; US
LANGER, Michael, R.; US
HARTWIG, Gregory, J.; US
Priority Data:
62/399,12323.09.2016US
Title (EN) UNSTRUCTURED NON-REPETITIVE POLYPEPTIDES HAVING LCST BEHAVIOR
(FR) POLYPEPTIDES NON RÉPÉTITIFS NON STRUCTURÉS AYANT UN COMPORTEMENT LCST
Abstract:
(EN) Described herein are unstructured polypeptides lacking any discernible repeat motif. Also described herein are fusion proteins including at least one of the unstructured polypeptides and at least one binding polypeptide. Further described are methods for treating a disease in a subject in need thereof. The methods may include administering to the subject an effective amount of the fusion protein.
(FR) L'invention concerne des polypeptides non structurés dépourvus de motif répétitif discernable. L'invention concerne également des protéines de fusion comprenant au moins l'un des polypeptides non structurés et au moins un polypeptide de liaison. L'invention concerne en outre des méthodes de traitement d'une maladie chez un sujet en ayant besoin. Les méthodes peuvent comprendre l'administration au sujet d'une quantité efficace de la protéine de fusion.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)