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1. (WO2018056795) COMPOSITION CONTAINING ENDOMETRIAL DECIDUAL CELLS FOR TREATING DAMAGE TO THE ENDOMETRIUM OR ENHANCING IMPLANTATION FUNCTIONS
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Pub. No.: WO/2018/056795 International Application No.: PCT/KR2017/010645
Publication Date: 29.03.2018 International Filing Date: 26.09.2017
IPC:
A61K 35/48 (2006.01) ,A61K 31/728 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
48
Reproductive organs; Embryos
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
726
Glycosaminoglycans, i.e. mucopolysaccharides
728
Hyaluronic acid
Applicants:
서울대학교 산학협력단 SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION [KR/KR]; 서울시 관악구 관악로 1 1, Gwanak-ro, Gwanak-gu, Seoul 08826, KR
Inventors:
구승엽 KU, Seung-Yup; KR
Agent:
손민 SON, Min; KR
Priority Data:
10-2016-012335026.09.2016KR
Title (EN) COMPOSITION CONTAINING ENDOMETRIAL DECIDUAL CELLS FOR TREATING DAMAGE TO THE ENDOMETRIUM OR ENHANCING IMPLANTATION FUNCTIONS
(FR) COMPOSITION CONTENANT DES CELLULES DÉCIDUALES DE L'ENDOMÈTRE VISANT À TRAITER DES LÉSIONS DE L'ENDOMÈTRE OU À AMÉLIORER LE PROCESSUS D'IMPLANTATION
(KO) 탈락막 자궁내막 세포를 포함하는 자궁내막 손상 치료 또는 착상능 증진용 조성물
Abstract:
(EN) The present invention relates to a composition containing endometrial decidual cells for treating damage to the endometrium or enhancing implantation functions, and particularly, to a pharmaceutical composition containing endometrial decidual cells and hyaluronic acid for treating damage to the endometrium, a method for treating damage to the endometrium using same, a composition for improving implantation functions, a composition for the prevention or treatment of infertility or subfertility, and a method for preventing or treating infertility or subfertility using same. The composition containing the endometrial decidual cells and hyaluronic acid, according to the present invention, can be injected into an individual having a damaged uterus to regenerate the damaged uterus and further improve implantation rate, and thus can be useful as the composition for treating damage to the endometrium, the composition for enhancing implantation functions, and the composition for the prevention or treatment of infertility or subfertility.
(FR) La présente invention concerne une composition contenant des cellules déciduales de l'endomètre visant à traiter des lésions de l'endomètre ou à améliorer le processus d'implantation, et, en particulier, une composition pharmaceutique contenant des cellules déciduales de l'endomètre et de l'acide hyaluronique visant à traiter des lésions de l'endomètre et une méthode de traitement de lésions de l'endomètre utilisant cette dernière, une composition visant à améliorer le processus d'implantation, une composition pour la prévention ou le traitement de l'infertilité ou d'une fertilité subnormale, et une méthode de prévention ou de traitement de l'infertilité ou de la fertilité subnormale utilisant cette dernière. La composition contenant les cellules déciduales de l'endomètre et l'acide hyaluronique, selon la présente invention, peut être injectée à un individu ayant un utérus endommagé afin de régénérer l'utérus endommagé et améliorer le taux d'implantation, et peut donc être utile en tant que composition pour le traitement de lésions de l'endomètre, en tant que composition pour améliorer les fonctions d'implantation, et en tant que composition pour la prévention ou le traitement de l'infertilité ou de la fertilité subnormale.
(KO) 본 발명은 탈락막 자궁내막 세포를 포함하는 자궁내막 손상의 치료 또는 착상능 증진용 조성물에 관한 것으로, 구체적으로 탈락막 자궁내막 세포 및 히알루론산을 포함하는 자궁내막 손상의 치료용 약학적 조성물 및 이를 이용한 자궁내막 손상의 치료방법, 착상능 증진용 조성물, 불임 또는 난임증의 예방 또는 치료용 조성물 및 이를 이용한 불임 또는 난임증의 예방 또는 치료방법에 관한 것이다 본 발명의 탈락막 자궁내막 세포 및 히알루론산을 포함하는 조성물은 자궁이 손상된 개체에 투여되어 손상된 자궁을 재생시키고 나아가 착상률을 개선시킬 수 있는바, 자궁내막 손상의 치료용 조성물, 착상능 증진용 조성물, 및 불임 또는 난임증의 예방 또는 치료용 조성물로 유용하게 이용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)