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1. (WO2018056583) COMPOSITION FOR SKIN WHITENING COMPRISING SH3BP4-INHIBITING MATERIAL, AND METHOD FOR SCREENING SH3BP4-INHIBITING MATERIAL
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/056583    International Application No.:    PCT/KR2017/008953
Publication Date: 29.03.2018 International Filing Date: 17.08.2017
IPC:
A61K 8/60 (2006.01), A61K 48/00 (2006.01), A61Q 19/02 (2006.01), G01N 33/50 (2006.01), G01N 33/68 (2006.01), C12Q 1/68 (2006.01)
Applicants: AMOREPACIFIC CORPORATION [KR/KR]; 106, Hangang-daero, Yongsan-gu, Seoul 04386 (KR)
Inventors: KIM, Kyuhan; (KR).
LEE, Tae Ryong; (KR).
CHO, Eun-Gyung; (KR)
Agent: KIM, Sun-young; (KR)
Priority Data:
10-2016-0122317 23.09.2016 KR
Title (EN) COMPOSITION FOR SKIN WHITENING COMPRISING SH3BP4-INHIBITING MATERIAL, AND METHOD FOR SCREENING SH3BP4-INHIBITING MATERIAL
(FR) COMPOSITION POUR LE BLANCHIMENT DE LA PEAU COMPRENANT UN COMPOSÉ INHIBANT SH3BP4 ET PROCÉDÉ DE CRIBLAGE DE COMPOSÉ INHIBANT SH3BP4
(KO) SH3BP4 억제 물질을 포함하는 피부 미백용 조성물 및 SH3BP4 억제 물질의 스크리닝 방법
Abstract: front page image
(EN)The present specification discloses a composition for skin whitening comprising an SH3BP4 expression- or activity-inhibiting material as an active ingredient, and a method for screening the SH3BP4 expression- or activity-inhibiting material. The composition comprising the SH3BP4 expression- or activity-inhibiting material as an active ingredient can provide an excellent whitening effect by decreasing the melanin content in the skin. Also, the screening method confirms the relative expression inhibition level of the SH3BP4 gene, thereby simply screening a skin whitening material.
(FR)La présente invention concerne une composition pour le blanchiment de la peau comprenant un composé inhibant l'expression ou l'activité de SH3BP4 en tant que principe actif, et un procédé de criblage de composé inhibant l'expression ou l'activité de SH3BP4. La composition comprenant le composé inhibant l'expression ou l'activité de SH3BP4 en tant que principe actif peut exercer un excellent effet de blanchiment en diminuant la teneur en mélanine dans la peau. De plus, le procédé de criblage confirme le niveau d'inhibition d'expression relatif du gène SH3BP4, ce qui permet de cribler simplement un composé de blanchiment de la peau.
(KO)본 명세서에는 SH3BP4 발현 또는 활성 억제 물질을 유효성분으로 포함하는 피부 미백용 조성물 및 SH3BP4 발현 또는 활성 억제 물질의 스크리닝 방법이 개시된다. 상기 SH3BP4 발현 또는 활성 억제 물질을 유효성분으로 포함하는 조성물은 피부 내 멜라닌 함량을 감소시켜 우수한 미백효과를 제공할 수 있다. 또한, 상기 스크리닝 방법에 따르면 SH3BP4 유전자의 상대적 발현 억제정도를 확인함으로써, 간편하게 피부 미백 물질을 스크리닝할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)