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1. (WO2018055136) USE OF HARRINGTONINES IN THE TREATMENT OF BREAST CANCER, IN PARTICULAR TRIPLE-NEGATIVE BREAST CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/055136    International Application No.:    PCT/EP2017/074135
Publication Date: 29.03.2018 International Filing Date: 22.09.2017
IPC:
A61K 31/55 (2006.01), A61P 35/00 (2006.01)
Applicants: ROBIN, Jean-Pierre [CH/CH]; (CH)
Inventors: ROBIN, Jean-Pierre; (CH).
RADOSEVIC, Nina; (FR).
ROBIN, Jean-Pierre; (CH).
PENAULT-LLORCA, Frédérique; (FR)
Agent: REGIMBEAU; 20, rue de Chazelles 75847 PARIS CEDEX 17 (FR)
Priority Data:
1658923 22.09.2016 FR
Title (EN) USE OF HARRINGTONINES IN THE TREATMENT OF BREAST CANCER, IN PARTICULAR TRIPLE-NEGATIVE BREAST CANCER
(FR) UTILISATION DES HARRINGTONINES DANS LE TRAITEMENT DU CANCER DU SEIN, NOTAMMENT TRIPLE-NÉGATIF
Abstract: front page image
(EN)The present invention relates to harringtonine, homoharringtonine and/or derivatives thereof, in particular compounds of formula 1a to 1g as defined in table 1, more particularly in the form of salt, preferably crystalline salt, for use in the treatment or prevention of breast cancer, in particular triple-negative breast cancer (TNBC).
(FR)La présente invention concerne l'harringtonine, l'homoharringtonine et/ouses dérivés, notamment les composés de formule Ia à Ig tels que définis dans le tableau 1, plus particulièrement sous forme de sel, de préférence cristallin, pour utilisation dans le traitement ou la prévention du cancer du sein, en particulier le cancer du sein «triple- négatif» (CSTN).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)