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1. (WO2018055060) FUSION COMPRISING A CELL PENETRATING PEPTIDE, A MULTI EPITOPE AND A TLR PEPTIDE AGONIST FOR TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/055060 International Application No.: PCT/EP2017/073954
Publication Date: 29.03.2018 International Filing Date: 21.09.2017
IPC:
A61K 39/00 (2006.01)
Applicants: AMAL THERAPEUTICS SA[CH/CH]; c/o Fondation pour Recherches Médicales 64 av. de la Roseraie 1205 Geneva, CH
Inventors: DEROUAZI, Madiha; CH
BELNOUE, Elodie; CH
Agent: VON STOSCH, Andreas; DE
EICHELBAUM, Kornelia; DE
LEHMBACHER, Michael; DE
HAHNER, Nadja; DE
Priority Data:
PCT/EP2016/07247521.09.2016EP
Title (EN) FUSION COMPRISING A CELL PENETRATING PEPTIDE, A MULTI EPITOPE AND A TLR PEPTIDE AGONIST FOR TREATMENT OF CANCER
(FR) FUSION COMPRENANT UN PEPTIDE DE PÉNÉTRATION CELLULAIRE, UN MULTI-ÉPITOPE ET UN AGONISTE DES PEPTIDES TLR POUR LE TRAITEMENT DU CANCER
Abstract:
(EN) The present invention provides a complex for use in the prevention and/or treatment of cancer, the complex comprising a) a cell penetrating peptide, b) at least one antigen or antigenic epitope, and c) at least one TLR peptide agonist, wherein the components a) - c) are covalently linked. In particular, compositions for use in the prevention and/or treatment of cancer, such as a pharmaceutical compositions and vaccines are provided.
(FR) La présente invention concerne un complexe destiné à être utilisé dans la prévention et/ou le traitement du cancer, le complexe comprenant a) un peptide de pénétration cellulaire, b) au moins un antigène ou un épitope antigénique, et c) au moins un agoniste des peptides TLR, les constituants a) à c) étant liés de manière covalente. L'invention concerne en particulier des compositions destinées à être utilisées dans la prévention et/ou le traitement du cancer, telles que des compositions pharmaceutiques et des vaccins.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)