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1. (WO2018054354) APPLICATION OF SRC HOMOLOGY REGION 2-CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AGONIST FOR IMPROVING FIBROSIS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/054354    International Application No.:    PCT/CN2017/102945
Publication Date: 29.03.2018 International Filing Date: 22.09.2017
IPC:
A61K 31/17 (2006.01), A61P 43/00 (2006.01), A61P 1/16 (2006.01), A61P 1/18 (2006.01), A61P 13/12 (2006.01), A61P 17/00 (2006.01)
Applicants: CHEN, Kuen-Feng [CN/CN]; (CN).
SHIAU, Chung-Wai [CN/CN]; (CN)
Inventors: CHEN, Kuen-Feng; (CN).
SHIAU, Chung-Wai; (CN).
SU, Tung-Hung; (CN).
WANG, Cheng-Yi; (CN)
Agent: DRAGON INTELLECTUAL PROPERTY LAW FIRM; 10F, Bldg. 2, Maples International Center No. 32 Xizhimen North Street, Haidian District Beijing 100082 (CN)
Priority Data:
62/398,274 22.09.2016 US
Title (EN) APPLICATION OF SRC HOMOLOGY REGION 2-CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AGONIST FOR IMPROVING FIBROSIS
(FR) APPLICATION D'UN AGONISTE DE PROTÉINE TYROSINE PHOSPHATASE 1 CONTENANT UNE RÉGION D'HOMOLOGIE SRC 2 POUR AMÉLIORER LA FIBROSE
(ZH) 含有SRC同源区2的蛋白酪氨酸磷酸酶-1激动剂用于改善纤维化的用途
Abstract: front page image
(EN)Provided is an application of an SRC homology region 2-containing protein tyrosine phosphatase-1 agonist as represented by formula (I) in preparation of drugs for treating and reducing fibrosis. Preferably, the agonist is SC-43; the fibrosis is skin sclerosis or cardiac, pulmonary, hepatic, pancreatic, or renal fibrosis.
(FR)L'invention concerne une application d'un agoniste de protéine tyrosine phosphatase 1 contenant une région d'homologie SRC 2 représenté par la formule (I) dans la préparation de médicaments pour le traitement et la réduction de la fibrose. De préférence, l'agoniste est SC-43, la fibrose est une sclérose cutanée ou une fibrose cardiaque, pulmonaire, hépatique, pancréatique ou rénale.
(ZH)提供一种含有SRC同源区2的蛋白酪氨酸磷酸酶-1激动剂式(I)在制备治疗、降低纤维化的药物中的用途,优选所述激动剂为SC-43,所述纤维化为皮肤硬化或心脏、肺、肝、胰或肾脏的纤维化。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)