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1. (WO2018053481) DETECTION OF ANALYTES WITH JANUS DROPLETS

Pub. No.:    WO/2018/053481    International Application No.:    PCT/US2017/052209
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Wed Sep 20 01:59:59 CEST 2017
IPC: G01N 33/543
G01N 33/50
G01N 33/53
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventors: SWAGER, Timothy, M.
ZHANG, Qifan
SAVAGATRUP, Suchol
Title: DETECTION OF ANALYTES WITH JANUS DROPLETS
Abstract:
Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).