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|1. (WO2018053215) BETA-LACTAMASE INHIBITOR COMPOUNDS|
|Applicants:||ENTASIS THERAPEUTICS LIMITED
DURAND-REVILLE, Thomas, Francois
VERHEIJEN, Jeroen, Cunera
BASARAB, Gregory, S.
|Title:||BETA-LACTAMASE INHIBITOR COMPOUNDS|
The present invention is directed to compounds which are beta-lactamase inhibitors. The compounds and their pharmaceutically acceptable salts are useful in combination with beta- lactam antibiotics, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R2, R3, R4, R5 and R6 are described herein.