WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018053209) HIGH PURITY RNA COMPOSITIONS AND METHODS FOR PREPARATION THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/053209 International Application No.: PCT/US2017/051674
Publication Date: 22.03.2018 International Filing Date: 14.09.2017
IPC:
C12N 15/10 (2006.01)
Applicants: MODERNATX, INC.[US/US]; 320 Bent Street Cambridge, MA 02141, US
Inventors: HOGE, Stephen; US
ISSA, William; US
MIRACCO, Edward J.; US
NELSON, Jennifer; US
RABIDEAU, Amy, E.; US
BUTORA, Gabor; US
Agent: LOCKHART, Helen C.; US
Priority Data:
62/394,71114.09.2016US
Title (EN) HIGH PURITY RNA COMPOSITIONS AND METHODS FOR PREPARATION THEREOF
(FR) COMPOSITIONS D'ARN DE HAUTE PURETÉ ET PROCÉDÉS POUR LEUR PRÉPARATION
Abstract: front page image
(EN) The invention relates to improved RNA compositions for use in therapeutic applications. The RNA compositions are particularly suited for use in human therapeutic application (e.g., in RNA therapeutics). The RNA compositions are made by inproved processes, in particular, improved in vitro-transcription (IVT) processes. The invention also relates to methods for producing and purifying RNA (e.g, therapeutic RNAs), as well as methods for using the RNA compositions and therapeutic applications thereof.
(FR) L'invention concerne des compositions d'ARN améliorées destinées à être utilisées dans des applications thérapeutiques. Les compositions d'ARN sont particulièrement appropriées pour une utilisation dans une application thérapeutique humaine (par exemple dans des agents thérapeutiques à ARN). Les compositions d'ARN sont préparées par des procédés améliorés, en particulier des processus de transcription in vitro améliorés (TIV). L'invention concerne également des procédés de production et de purification d'ARN (par exemple des ARN thérapeutiques), ainsi que des procédés d'utilisation des compositions d'ARN et leurs applications thérapeutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)