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1. (WO2018053052) DACTINOMYCIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/053052    International Application No.:    PCT/US2017/051427
Publication Date: 22.03.2018 International Filing Date: 13.09.2017
IPC:
A61K 47/10 (2017.01), A61K 9/50 (2006.01), A61K 9/14 (2006.01), A61K 9/16 (2006.01)
Applicants: RASNA RESEARCH INC. [US/US]; 420 Lexington Avenue Suite 2525 New York, NY 10170 (US)
Inventors: SHAILUBHAI, Kunwar; (US)
Agent: ELRIFI, Ivor R.; (US).
ERLACHER, Heidi A.; (US).
PAXTON, Thomas; (US).
STOCK, Christina K.; (US)
Priority Data:
62/394,104 13.09.2016 US
62/444,330 09.01.2017 US
62/500,459 02.05.2017 US
Title (EN) DACTINOMYCIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA
(FR) COMPOSITIONS DE DACTINOMYCINE ET MÉTHODES DE TRAITEMENT DU SYNDROME MYÉLODYSPLASIQUE ET DE LA LEUCÉMIE MYÉLOÏDE AIGUË
Abstract: front page image
(EN)The disclosure provides compositions comprising dactinomycin, formulated for delivery by nanoparticle, and methods for treating a myelodysplastic syndrome (MDS) or cancer, for example, NPM1-mutated acute myeloid leukemia (AML), by administration of the compositions of the disclosure.
(FR)L'invention concerne des compositions comprenant de la dactinomycine, formulées pour une administration par des nanoparticules, et des méthodes de traitement d'un syndrome myélodysplasique (MDS) ou le cancer, par exemple, la leucémie myéloïde aiguë (LMA) à gène NPM1 muté, par administration des compositions de l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)