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1. (WO2018052818) ANTI-PD-1 ANTIBODIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/052818    International Application No.:    PCT/US2017/050851
Publication Date: 22.03.2018 International Filing Date: 09.09.2017
IPC:
C07K 16/28 (2006.01), C07K 16/18 (2006.01), C12P 21/08 (2006.01), A61K 49/16 (2006.01), A61K 51/10 (2006.01), A61K 39/395 (2006.01), A61K 47/68 (2017.01), G01N 33/563 (2006.01)
Applicants: HENLIX, INC. [US/US]; 46421 Landing Pkwy Fremont, CA 94538 (US).
HENLIX BIOTECH CO., LTD.; 5F., No.36.Ln.15,Sec.6 Minquan E. Rd., Taipei 11494 (TW)
Inventors: JIANG, Weidong; (US).
LIN, Pei-Hua; (US).
TSENG, Chi-Ling; (US)
Agent: LEI, Fang; (US)
Priority Data:
62/519,590 14.06.2017 US
62/395,832 16.09.2016 US
Title (EN) ANTI-PD-1 ANTIBODIES
(FR) ANTICORPS ANTI-PD-1
Abstract: front page image
(EN)Provided are anti-PD-1 antibodies, and antigen binding fragments thereof. Also provided are isolated nucleic acid molecules that encode the anti-PD-1 antibodies or antigen binding fragments thereof, related expression vectors, and host cells. Provided are methods of making anti-PD-1 antibodies, and antigen binding fragments thereof. Also provided are related pharmaceutical compositions and methods of their use to treat subjects.
(FR)L'invention concerne des anticorps anti-PD-1, et des fragments de liaison à l'antigène de ceux-ci. L'invention concerne également des molécules d'acides nucléiques isolées qui codent pour les anticorps anti-PD1 ou des fragments de liaison à l'antigène de ceux-ci, des vecteurs d'expression associés, et des cellules hôtes. L'invention concerne des procédés de production des anticorps anti-VEGFR1 et des fragments de liaison à l'antigène de ceux-ci. L'invention concerne également des compositions pharmaceutiques associées et leurs procédés d'utilisation pour traiter des sujets.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)