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1. (WO2018052773) PYRIDINE AND PYRAZINE COMPOUNDS AS INHIBITORS OF RIPK2

Pub. No.:    WO/2018/052773    International Application No.:    PCT/US2017/050200
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Thu Sep 07 01:59:59 CEST 2017
IPC: C07D 401/04
C07D 403/04
A61K 31/4439
A61P 29/00
A61P 35/00
A61P 37/06
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Inventors: PADYANA, Anil K.
SPENCER, Elizabeth
MILLER, Craig Andrew
LIU, Pingrong
CUI, Jianwen
GAO, Donghong Amy
MCKIBBEN, Bryan Patrick
RAZAVI, Hossein
RUPPEL, Sabine
Title: PYRIDINE AND PYRAZINE COMPOUNDS AS INHIBITORS OF RIPK2
Abstract:
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, X, Y, and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes