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1. (WO2018052772) HETEROARYL CARBOXAMIDE COMPOUNDS AS INHIBITORS OF RIPK2

Pub. No.:    WO/2018/052772    International Application No.:    PCT/US2017/050197
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Thu Sep 07 01:59:59 CEST 2017
IPC: C07D 231/12
C07D 403/04
C07D 417/04
C07D 417/14
C07D 471/04
C07D 487/04
A61K 31/437
A61P 37/00
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Inventors: PADYANA, Anil K.
ZHANG, Zhonghua
RUPPEL, Sabine
YU, Maolin
LIU, Pingrong
MILLER, Craig Andrew
Title: HETEROARYL CARBOXAMIDE COMPOUNDS AS INHIBITORS OF RIPK2
Abstract:
The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, X, Y, and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes