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1. (WO2018052419) SYSTEM AND METHOD FOR IN SITU VISUALIZATION OF NERVES USING TARGETED FLUORESCENT MOLECULES

Pub. No.:    WO/2018/052419    International Application No.:    PCT/US2016/051820
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Fri Sep 16 01:59:59 CEST 2016
IPC: A61K 49/00
A61B 5/00
Applicants: AVENT, INC.
Inventors: MADSEN, Arne J.
HSU, Kenneth C.
Title: SYSTEM AND METHOD FOR IN SITU VISUALIZATION OF NERVES USING TARGETED FLUORESCENT MOLECULES
Abstract:
The present invention is directed to a system and method for enhancing in situ visualization of a target site within a patient during a medical procedure using fluorescence. As such, the system includes a plurality of fluorescent molecules (12) configured to selectively target and bind to one or more locations at the target site (16) within the patient and a delivery mechanism (20) for delivering the fluorescent molecules into the patient. In addition, the system includes a detection device (26) configured to generate a detectable signal containing information relating to the target site and send the detectable signal to an imaging system for viewing by a user, such as a physician. Thus, the fluorescent molecules enhance in situ visualization of the target site when viewed through the skin of the patient.