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1. (WO2018052182) AGENT COMPRISING MESENCHYMAL STEM CELL OR AGRP FOR TREATMENT OF DEGENERATIVE BRAIN DISEASE THROUGH INCREASE IN UBIQUITIN PROTEASOME ACTIVITY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/052182    International Application No.:    PCT/KR2017/007174
Publication Date: 22.03.2018 International Filing Date: 05.07.2017
IPC:
A61K 35/28 (2006.01), A61K 35/51 (2015.01), A61K 35/50 (2006.01), A61K 35/35 (2015.01), A61K 48/00 (2006.01), A23L 33/18 (2016.01), A23L 33/13 (2016.01), G01N 33/68 (2006.01)
Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION [KR/KR]; 48, Itaewon-ro 55-gil Yongsan-gu, Seoul 04348 (KR)
Inventors: CHANG, Jong Wook; (KR).
NA, Duk L.; (KR).
LEE, Na Kyung; (KR)
Agent: Y.P.LEE, MOCK & PARTNERS; 12F Daelim Acrotel, 13 Eonju-ro 30-gil Gangnam-gu, Seoul 06292 (KR)
Priority Data:
10-2016-0118204 13.09.2016 KR
10-2017-0085410 05.07.2017 KR
Title (EN) AGENT COMPRISING MESENCHYMAL STEM CELL OR AGRP FOR TREATMENT OF DEGENERATIVE BRAIN DISEASE THROUGH INCREASE IN UBIQUITIN PROTEASOME ACTIVITY
(FR) AGENT COMPRENANT UNE CELLULE SOUCHE MÉSENCHYMATEUSE OU AGRP POUR LE TRAITEMENT D'UNE MALADIE DE DÉGÉNÉRESCENCE DU CERVEAU PAR AUGMENTATION DE L'ACTIVITÉ UBIQUITINE/PROTÉASOME
(KO) 중간엽 줄기세포 또는 AgRP를 포함하는 유비퀴틴 프로테아좀 활성 증가를 통한 퇴행성 뇌질환 치료제
Abstract: front page image
(EN)A composition comprising mesenchymal stem cells, or AgRP or an active fragment thereof according to one aspect has the effect of being useful for preventing, treating, or alleviating a disease associated with decrease activity of ubiquitin proteasome, for example, a degenerative brain disease by increasing the activity of ubiquitin proteasome.
(FR)L'invention concerne une composition comprenant des cellules souches mésenchymateuses, ou AgRP ou un fragment actif de celui-ci selon un aspect, qui a pour effet d'être utile pour prévenir, traiter ou atténuer une maladie associée à une diminution de l'activité ubiquitine/protéasome par exemple, une maladie de dégénérescence du cerveau par augmentation de l'activité ubiquitine/protéasome.
(KO)일 양상에 따른 중간엽줄기세포, AgRP 또는 그의 활성 단편을 포함하는 조성물은 유비퀴틴 프로테아좀의 활성을 증가시켜 유비퀴틴 프로테아좀 활성 감소와 관련된 질환, 예를 들면, 퇴행성 뇌질환의 예방, 치료, 또는 개선에 유용하게 사용될 수 있는 효과가 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)