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1. (WO2018052094) METHOD FOR ENHANCING RETENTIVITY OF PEPTIDE IN BLOOD
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Pub. No.: WO/2018/052094 International Application No.: PCT/JP2017/033348
Publication Date: 22.03.2018 International Filing Date: 14.09.2017
IPC:
C07K 14/575 (2006.01) ,A61K 38/28 (2006.01) ,A61K 38/30 (2006.01) ,A61K 47/61 (2017.01) ,A61P 3/10 (2006.01) ,C07K 14/62 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
28
Insulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
30
Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
[IPC code unknown for A61K 47/61]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
62
Insulins
Applicants:
生化学工業株式会社 SEIKAGAKU CORPORATION [JP/JP]; 東京都千代田区丸の内一丁目6番1号 6-1, Marunouchi 1-chome, Chiyoda-ku, Tokyo 1000005, JP
Inventors:
高津 吉広 TAKATSU, Yoshihiro; JP
大瀧 徹也 OTAKI, Tetsuya; JP
平山 哲也 HIRAYAMA, Tetsuya; JP
福嶋 正信 FUKUSHIMA, Masanobu; JP
市川 めぐみ ICHIKAWA, Megumi; JP
Agent:
佐貫 伸一 SANUKI, Shinichi; JP
丹羽 武司 NIWA, Takeshi; JP
Priority Data:
2016-17968414.09.2016JP
Title (EN) METHOD FOR ENHANCING RETENTIVITY OF PEPTIDE IN BLOOD
(FR) PROCÉDÉ D'AMÉLIORATION DE LA RETENTIVITÉ D'UN PEPTIDE DANS LE SANG
(JA) ペプチドの血中滞留性を増強させる方法
Abstract:
(EN) Provided is a means for enhancing the retentivity of a peptide in blood. The retentivity of a peptide in blood is enhanced by binding the peptide to glycosaminoglycan via a linker to form a complex comprising the peptide and glycosaminoglycan.
(FR) L'invention concerne un moyen pour améliorer la capacité de rétention d'un peptide dans le sang. La retentivité d'un peptide dans le sang est améliorée par liaison du peptide au glycosaminoglycane par l'intermédiaire d'un lieur pour former un complexe comprenant le peptide et le glycosaminoglycane.
(JA) ペプチドの血中滞留性を増強させる手段を提供する。リンカーを介してグリコサミノグリカンとペプチドを結合させてグリコサミノグリカンとペプチドを含む複合体を形成することにより、ペプチドの血中滞留性を増強する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)