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1. (WO2018052066) HETEROCYCLIC AMIDE COMPOUND
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/052066    International Application No.:    PCT/JP2017/033214
Publication Date: 22.03.2018 International Filing Date: 14.09.2017
IPC:
C07D 401/04 (2006.01), A61K 31/4439 (2006.01), A61K 31/444 (2006.01), A61K 31/506 (2006.01), A61P 35/00 (2006.01), A61P 43/00 (2006.01), C07D 401/14 (2006.01), C07D 403/04 (2006.01), C07D 403/14 (2006.01), C07D 405/14 (2006.01), C07D 409/14 (2006.01), C07D 417/14 (2006.01), C12N 9/99 (2006.01)
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP)
Inventors: HIRAYAMA, Takaharu; (JP).
HIRATA,Yasuhiro; (JP).
TOMINARI, Yusuke; (JP).
IWAMURA, Naoki; (JP).
SASAKI, Yusuke; (JP).
ASANO, Moriteru; (JP).
TAKAGI, Terufumi; (JP).
OKANIWA, Masanori; (US).
YOSHIDA, Masato; (JP).
IMAMURA, Shinichi; (JP)
Agent: TAKASHIMA, Hajime; (JP).
KAMADA, Mitsunori; (JP)
Priority Data:
2016-180749 15.09.2016 JP
Title (EN) HETEROCYCLIC AMIDE COMPOUND
(FR) COMPOSÉ AMIDE HÉTÉROCYCLIQUE
(JA) 複素環アミド化合物
Abstract: front page image
(EN)Provided is a heterocyclic compound that can have a PRS inhibitory effect and is expected to be of use as a prophylaxis or a therapeutic agent for PRS-related diseases, including cancer. A compound or a salt thereof, said compound being expressed by formula (I) (wherein each symbol is as indicated in the specification).
(FR)L’invention a pour objet de fournir un composé amide hétérocyclique qui peut présenter une action inhibitrice de prolyl-tARN synthétase, et qui peut être mis en œuvre en tant qu’agent de prévention ou de traitement d’affections liées à une prolyl-tARN synthétase dont le cancer. Plus précisément, l’invention concerne un composé représenté par la formule (I) (dans la formule, chaque symbole est tel que défini dans la description.) ou un sel de celui-ci.
(JA)PRS阻害作用を有し得、癌を含むPRS関連疾患等の予防または治療剤として有用であることが期待される複素環アミド化合物を提供すること。下式(I):〔式中、各記号は、明細書に記載の通りである。〕 で表される化合物またはその塩。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)