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1. (WO2018051295) NON-SAPONIFIABLE COMPOUNDS OF NATURAL LIPIDS FOR USE IN THE TREATMENT OF TUMOUR PATHOLOGIES
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Pub. No.: WO/2018/051295 International Application No.: PCT/IB2017/055623
Publication Date: 22.03.2018 International Filing Date: 18.09.2017
IPC:
A61K 35/36 (2015.01) ,A61K 36/63 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
36
Skin; Hair; Nails; Sebaceous glands; Cerumen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
63
Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
CODEX V SRL [IT/IT]; Circonvallazione A. Gramsci 26 04010 Cori (LT), IT
Inventors:
DE GREGORIO, Chiara; IT
Agent:
BORSANO, corrado; IT
BARONI, Matteo; IT
CAMOLESE, Marco; IT
REPOSIO, Giancarlo; IT
Priority Data:
10201600009375819.09.2016IT
Title (EN) NON-SAPONIFIABLE COMPOUNDS OF NATURAL LIPIDS FOR USE IN THE TREATMENT OF TUMOUR PATHOLOGIES
(FR) COMPOSÉS NON SAPONIFIABLES DE LIPIDES NATURELS DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT DE PATHOLOGIES TUMORALES
Abstract:
(EN) The present invention relates to the use of non-saponifiable moieties obtained from natural, plant and/or animal lipids, for the treatment of tumour diseases caused by the permanent (or chronic) alteration (or imbalance) of the normal physiological equilibrium of the steroidal balance in a patient suffering from this chronic condition. In particular, the invention relates to a pharmaceutical composition comprising said non-saponifiable moieties for use in the treatment of those tumour diseases, lung tumours and/or vulvar tumors and/or mammary tumors and/or shell carcinomas and/or melanomas, which are caused by permanent (or chronic) alteration (or unbalance) of the natural physiological equilibrium of the steroidal balance in a patient suffering from said pathology, and of the chronic lesions associated with the same which determine them. Said pharmaceutical composition is particularly adapted for transdermal and/or transmucosal topical administration.
(FR) La présente invention concerne l'utilisation de fractions non saponifiables obtenues à partir de lipides naturels, végétaux et/ou animaux, pour le traitement de maladies tumorales provoquées par la modification (ou le déséquilibre) permanente (ou chronique) de l'équilibre physiologique normal de l'équilibre stéroïdien chez un patient atteint de cette pathologie chronique. En particulier, l'invention concerne une composition pharmaceutique comprenant lesdites fractions non saponifiables, destinée à être utilisée dans le traitement de ces maladies tumorales, de tumeurs pulmonaires et/ou de tumeurs vulvaires et/ou de tumeurs mammaires et/ou de carcinomes et/ou de mélanomes, qui sont provoqués par une modification (ou déséquilibre) permanente (ou chronique) de l'équilibre physiologique naturel de l'équilibre stéroïdien chez un patient atteint de ladite pathologie, et de lésions chroniques associées à celle-ci qui les déterminent. Ladite composition pharmaceutique est particulièrement appropriée pour une administration transdermique et/ou transmucosale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: Italian (IT)