GB2017052707 HUMAN OTIC PROGENITOR IDENTIFICATION AND ISOLATION

1. (WO2018051092) HUMAN OTIC PROGENITOR IDENTIFICATION AND ISOLATION

National Phase

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Pub. No.:		WO/2018/051092		International Application No.:		PCT/GB2017/052707
Publication Date:		22.03.2018		International Filing Date:		14.09.2017

IPC:

G01N 33/569 (2006.01), C07K 16/28 (2006.01), C07K 16/30 (2006.01), C12N 5/0793 (2010.01), C12N 5/0797 (2010.01), C12N 5/074 (2010.01)

Applicants:

THE UNIVERSITY OF SHEFFIELD [GB/GB]; Firth Court Western Bank Sheffield S10 2TN (GB)

Inventors:

RIVOLTA, Carlos Marcelo Nicolas; (GB).
BODDY, Sarah Louise; (GB)

Agent:

HGF LTD; Document Handling (HGF) York 1 City Walk Leeds Yorkshire LS11 9DX (GB)

Priority Data:

1615714.1

15.09.2016

Title

(EN) HUMAN OTIC PROGENITOR IDENTIFICATION AND ISOLATION
(FR) IDENTIFICATION ET ISOLATION DE PROGÉNITEUR OTIQUE HUMAIN

Abstract:

(EN)The present invention relates generally to the identification and isolation of human otic progenitor cells. More specifically, the present invention relates to a method of using cell markers to identify and isolate human otic progenitor cells from a mixed population of cells, methods of enrichment and production of human otic progenitor cells, and associated kits for use in identification and/or isolation of human otic progenitor cells, wherein the cell markers are selected from SSEA1 (CD15), disialoganglioside GD3, TRA-2-49 (liver/bone/ kidney alkaline phosphatase), SSEA4, ganglioside GD2 and CD141.
(FR)La présente invention concerne de manière générale l'identification et l'isolement de cellules progénitrices otiques humaines. Plus spécifiquement, la présente invention concerne un procédé d'utilisation de marqueurs cellulaires pour identifier et isoler des cellules progénitrices otiques humaines à partir d'une population mixte de cellules, des procédés d'enrichissement et de production de cellules progénitrices otiques humaines, et des kits associés destinés à être utilisés dans l'identification et/ou l'isolement de cellules progénitrices otiques humaines, les marqueurs cellulaires étant choisis parmi SSEA1 (CD15), le disialoganglioside GD3, la TRA-2-49 (foie/os/phosphatase alcaline rénale), SSEA4, le ganglioside GD2 et le CD141.

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).

Publication Language:	English (EN)
Filing Language:	English (EN)

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