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1. (WO2018051071) DETECTION AND TREATMENT OF MICROSPORIDIAN INFECTION

Pub. No.:    WO/2018/051071    International Application No.:    PCT/GB2017/052676
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Wed Sep 13 01:59:59 CEST 2017
IPC: A61K 39/395
C12Q 1/68
C12N 15/11
G01N 33/53
Applicants: BENCHMARK ANIMAL HEALTH LIMITED
Inventors: SCHOLZ, Felix
RODGER, Hamish
Title: DETECTION AND TREATMENT OF MICROSPORIDIAN INFECTION
Abstract:
An isolated or synthetic nucleic acid from having a sequence selected from the group consisting of SEQ ID NOs: 9, 13 and 1-8, or a homologues thereof, an isolated or synthetic nucleic acid complementary to a sequence selected from the group consisting of SEQ ID NOs: 1-14, or a homologues thereof, an isolated polypeptide encoded by the nucleic acid, or an antibody that binds thereto, may be used as an immunogenic composition or diagnostic, or in a method of treatment or prevention, in respect of a microsporidian infection, in particular a Tetramicra brevifilum infection in animals, particularly fish. Additionally, methods of testing an agent for the prevention and/or treatment of a microsporidian infection, preferably a Tetramicra brevifilum infection, and kits for screening for a microsporidian infection, are provided.