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1. (WO2018050833) IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS DIRECTED AGAINST MACROPHAGE MIGRATION INHIBITORY FACTOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/050833    International Application No.:    PCT/EP2017/073302
Publication Date: 22.03.2018 International Filing Date: 15.09.2017
IPC:
C07K 16/18 (2006.01), C07K 16/24 (2006.01), A61K 39/395 (2006.01)
Applicants: ABLYNX NV [BE/BE]; Technologiepark 21 9052 Ghent-Zwijnaarde (BE).
VIB VZW [BE/BE]; Rijvisschestraat 120 9052 Gent (BE).
VRIJE UNIVERSITEIT BRUSSEL [BE/BE]; Pleinlaan 2 1050 Brussel (BE)
Inventors: VANLANDSCHOOT, Peter; (BE).
CABRITO, Ines; (PT).
STIJLEMANS, Benoît; (BE).
SPARKES, Amanda; (BE).
VAN GINDERACHTER, Jo; (BE).
DE BAETSELIER, Patrick; (BE)
Agent: HOFFMANN EITLE PATENT- UND RECHTSANWÄLTE PARTMBB, ASSOCIATION NO. 151; Arabellastraße 30 81925 Munich (DE).
ZANGS, Rainer E.; (DE).
KINDLER, Matthias; (DE).
FRANK, Veit Peter; (DE).
POLZ, Leo; (DE).
STEIN-DRÄGER, Christiane; (DE).
AVERY, Stephen John; (DE).
LETHEM, David James; (DE).
MARSH, Roy David; (DE).
MITCHELL, Alan; (DE).
FURLONG, Christopher Heinrich; (DE).
BAUSCH, Thorsten; (DE).
TAORMINO, Joseph Paul; (DE).
KLUSMANN, Peter; (DE).
SCHWEIGHART, Peter; (DE).
WOLF, Matthias; (DE).
SIEGERT, Georg; (DE).
MAYRHOFER, Stefan; (DE).
STRATMANN, Klemens; (DE).
WIEDEMANN, Peter; (DE).
VON KUROWSKI, Lorenz; (DE).
BECHER, Claus Thomas; (DE).
SPILGIES, Jan-Hendrik; (DE).
RENKEN, Joachim; (DE).
ENGELHARD, Elisabeth; (DE).
BACHELIN, Karl Martin Raimund; (DE).
DISSER, Stephan; (DE).
VAN BOUWELEN, Franciscus Maria; (DE).
FÜCHSLE, Kathrin; (DE).
CIESLA, Ulrike; (DE).
SCHÖN, Anne Katrin; (DE).
VOCKE, Henrik; (DE).
GÖRG, Andreas; (DE).
GARBERG, Morten; (DE).
RUSSELL, John Alistair; (DE).
SPROSTON, David; (DE).
THIRLWELL, Karen; (DE).
SCHEIBLE, Dominik; (DE).
VOS, Bianca-Lucia; (DE).
DOUXCHAMPS, Nicolas; (DE).
STEFFERL, Andreas; (DE).
GOLLER, Daniel; (DE).
PRUSS, Timo; (DE).
WERNER-JONES, Leonard L.; (DE).
BACCELLI, Michele; (DE).
MÜLLER, Markus Georg; (DE).
MUNCKE, Nadja; (DE).
CORNEO, Giovanni; (DE).
STREGE, Christine; (DE).
DRAGOSAVAC, Marko; (DE).
BIRKETT, Matthew; (DE).
ZILLIES, Jan Carl; (DE).
GROHS, Daniel; (DE).
MULHERN, Declan; (DE).
GRIMM, Stephan; (DE).
TILLMANN, Volker; (DE).
OGLE, James Matthew; (DE).
GLAS, Johannes Dominik; (DE).
STEINMÜLLER, Stephan; (DE).
BENEDETTO, Marco; (DE).
LEVINE, Benjamin; (DE).
JONES, Mark A. G.; (DE).
GRAEBER, Jens; (DE).
FUSTER, Gustavo; (DE).
ESSER, Axel T.; (DE).
SCHIEREN, Roland; (DE).
RECKENTHÄLER, Peter; (DE).
CATANIA, Olivier; (DE).
DÖRFEL, Katrin; (DE).
WEINMANN, Lasse; (DE).
SASSE, Stefan; (DE).
MACHOTTA, Axel; (DE).
SCHREIBER, Christian; (DE).
WYDER, Thomas; (DE).
WEIGEL-KRUSEMARCK, Michaela; (DE).
MÜLLER, Michael; (DE).
LEWIS, Debra Louise; (DE).
PAETZOLD, Helge; (DE).
SPIRKOSKA, Danche; (DE)
Priority Data:
62/394,927 15.09.2016 US
Title (EN) IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS DIRECTED AGAINST MACROPHAGE MIGRATION INHIBITORY FACTOR
(FR) DOMAINES VARIABLES UNIQUES D'IMMUNOGLOBULINE DIRIGÉS CONTRE LE FACTEUR INHIBITEUR DE LA MIGRATION DES MACROPHAGES
Abstract: front page image
(EN)The present invention relates to immunoglobulin single variable domains that bind MIF and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes.
(FR)La présente invention concerne des domaines variables uniques d'immunoglobulines qui se lient au MIF et plus particulièrement des polypeptides qui comprennent ou consistent essentiellement en un ou plusieurs de ces domaines variables uniques d'immunoglobulines; des acides nucléiques codant de tels polypeptides; des procédés de préparation de tels polypeptides; des compositions et en particulier des compositions pharmaceutiques qui comprennent de tels polypeptides, à des fins prophylactiques, thérapeutiques ou diagnostiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)