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1. (WO2018050826) MAGNETIC PARTICLE-BINDING PEPTIDES

Pub. No.:    WO/2018/050826    International Application No.:    PCT/EP2017/073291
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Sat Sep 16 01:59:59 CEST 2017
IPC: C07K 14/00
Applicants: TECHNISCHE UNIVERSITÄT MÜNCHEN
KARLSRUHER INSTITUT FÜR TECHNOLOGIE
Inventors: BERENSMEIER, Sonja
BLANK-SHIM, Silvia
SCHWAMINGER, Sebastian
FRAGA GARCIA, Paula
WENZEL, Wolfgang
FINK, Karin
ANAND, Priya
BORKOWSKA-PANEK, Monika
Title: MAGNETIC PARTICLE-BINDING PEPTIDES
Abstract:
The present invention relates to a peptide consisting of a sequence of 5 to 30, preferably 6 to 12, most preferably 10 to 12 amino acids, wherein (a) at least 2/3 of said amino acids have a functional group or side chain which is negatively charged at neutral pH; (b) amino acids which do not have a functional group or side chain which is negatively charged at neutral pH, if present, meet one or both of requirements (i) and (ii): (i) none of them has a functional group or side chain which is positively charged at neutral pH; and (ii) at least one of them has a side chain which does not bear a net charge at neutral pH or which has a functional group or side chain that does not bear a net charge at neutral pH.