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1. (WO2018050672) METHOD FOR POST-PROCESSING MRI IMAGES TO OBTAIN HEPATIC PERFUSION AND TRANSPORT PARAMETERS

Pub. No.:    WO/2018/050672    International Application No.:    PCT/EP2017/072974
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Thu Sep 14 01:59:59 CEST 2017
IPC: G01R 33/56
G01R 33/563
A61B 5/00
Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
UNIVERSITÉ PARIS DIDEROT - PARIS 7
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
ASSISTANCE PUBLIQUE – HÔPITAUX DE PARIS
Inventors: LEPORQ, Benjamin
DAIRE, Jean-Luc
VAN BEERS, Bernard
Title: METHOD FOR POST-PROCESSING MRI IMAGES TO OBTAIN HEPATIC PERFUSION AND TRANSPORT PARAMETERS
Abstract:
The invention relates to liver diseases. Liver diseases notably encompass chronic liver disease and liver cancer (a liver primitive cancer or metastasis). There is therefore a need to be able to extract biomarkers for subjects to suffer from this disease. As a consequence, the inventors worked on a method for post-processing images of a region of interest to obtain at least one perfusion parameter and at least one transport parameter. Such method enables to obtain a method which can be implemented on computer and provides access to relevant parameters for liver diseases in an easier and more accurate way. This method may be applied for predicting that a subject is at risk of suffering from such disease, diagnosing a disease, identifying a therapeutic or a biomarker and screening compounds useful as a medicine.