Search International and National Patent Collections

1. (WO2018050299) SYSTEMS, METHODS, AND GENE SIGNATURES FOR PREDICTING A BIOLOGICAL STATUS OF AN INDIVIDUAL

Pub. No.:    WO/2018/050299    International Application No.:    PCT/EP2017/063073
Publication Date: Fri Mar 23 00:59:59 CET 2018 International Filing Date: Wed May 31 01:59:59 CEST 2017
IPC: G06F 19/18
G06F 19/24
C12Q 1/68
G06F 19/00
Applicants: PHILIP MORRIS PRODUCTS S.A.
POUSSIN, Carine
BELCASTRO, Vincenzo
MARTIN, Florian
BOUE, Stephanie
PEITSCH, Manuel, Claude
Inventors: POUSSIN, Carine
BELCASTRO, Vincenzo
MARTIN, Florian
BOUE, Stephanie
PEITSCH, Manuel, Claude
Title: SYSTEMS, METHODS, AND GENE SIGNATURES FOR PREDICTING A BIOLOGICAL STATUS OF AN INDIVIDUAL
Abstract:
Systems and methods for assessing a subject's sample to predict the subject's biological status, such as a smoker status. The computer-implemented method includes receiving, by a computer system including at least one hardware processor, a data set associated with the sample. The data set comprises quantitative expression data for a set of genes less than a whole genome, the set of genes comprising AHHR, CDKN1C, LRRN3, PID1, GPR15, SASH1, CLEC10A, LINC00599, P2RY6, DSC2, F2R, SEMA6B, and TLR5. The at least one hardware processor generates a score based on the quantitative expression data for the set of genes in the received data set, wherein the score is based on fewer than 40 genes and is indicative of a predicted smoking status of the subject.