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1. (WO2018049293) BIOCOMPATIBLE POLYMER AND MAGNESIUM FOR REGENERATION OF ARTICULAR SURFACES IN THE TEMPOROMANDIBULAR JOINT
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Pub. No.: WO/2018/049293 International Application No.: PCT/US2017/050882
Publication Date: 15.03.2018 International Filing Date: 11.09.2017
IPC:
A61F 2/30 (2006.01) ,A61L 31/12 (2006.01) ,A61K 35/32 (2015.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
30
Joints
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
12
Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
32
Bones; Tendons; Teeth; Cartilage
Applicants: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION[US/US]; 1st Floor Gardner Steel Conference Center 130 Thackeray Avenue Pittsburgh, Pennsylvania 15260, US
Inventors: ALMARZA, Alejandro; US
CHIN, Adam; US
TABOAS, Juan; US
WANG, Yadong; US
Agent: MARMO, Carol A.; US
LEVY, Philip E.; US
Priority Data:
62/385,36309.09.2016US
Title (EN) BIOCOMPATIBLE POLYMER AND MAGNESIUM FOR REGENERATION OF ARTICULAR SURFACES IN THE TEMPOROMANDIBULAR JOINT
(FR) POLYMÈRE ET MAGNÉSIUM BIOCOMPATIBLES POUR LA RÉGÉNÉRATION DE SURFACES ARTICULAIRES DANS L'ARTICULATION TEMPORO-MANDIBULAIRE
Abstract:
(EN) The invention relates to biodegradable, biocompatible materials to promote regeneration of articular surfaces in the temporomandibular joint and, more particularly, to biomaterials and methods for facilitating fibrochondrocyte and chondrocyte growth in in-vitro and in-vivo environments. The materials include magnesium in solid form and polymer. The materials are effective to grow and regenerate fibrochondrocyte and chondrocyte cells, and restore bone cells.
(FR) L'invention concerne des matériaux biocompatibles et biodégradables pour favoriser la régénération de surfaces articulaires dans l'articulation temporo-mandibulaire et, plus particulièrement, à des biomatériaux et à des procédés pour faciliter la croissance de fibrochondrocytes et de chondrocytes dans des environnements in-vitro et in-vivo. Les matériaux incluent le magnésium sous forme solide et un polymère. Les matériaux sont efficaces pour faire croître et régénérer des cellules chondrocytes et des cellules fibrochondrocytes, et restaurer des cellules osseuses.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)