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1. (WO2018049118) HSP FUSION PROTEIN WITH ANTI-CHEMOREPELLANT AGENT FOR TREATMENT OF CANCER

Pub. No.:    WO/2018/049118    International Application No.:    PCT/US2017/050618
Publication Date: Fri Mar 16 00:59:59 CET 2018 International Filing Date: Sat Sep 09 01:59:59 CEST 2017
IPC: A61K 35/74
A61K 35/00
A61P 31/00
C07K 19/00
A61K 31/33
Applicants: THE GENERAL HOSPITAL CORPORATION
Inventors: POZNANSKY, Mark C.
GELFAND, Jeffrey A.
Title: HSP FUSION PROTEIN WITH ANTI-CHEMOREPELLANT AGENT FOR TREATMENT OF CANCER
Abstract:
This disclosure is directed to immune treatment of a disease (e.g., cancer) using a fusion protein in combination with an anti-chemorepellant agent. In particular, the fusion protein comprises an antigen-binding domain (e.g., an antibody or antibody fragment) and a stress protein domain.