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1. (WO2018049015) COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PD-1 ANTAGONISTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/049015    International Application No.:    PCT/US2017/050457
Publication Date: 15.03.2018 International Filing Date: 07.09.2017
IPC:
A61K 31/69 (2006.01), A61K 45/06 (2006.01), A61K 39/00 (2006.01)
Applicants: TRUSTEES OF TUFTS COLLEGE [US/US]; Office of Technology and Industry Collaboration 136 Harrison Avenue, 75K-401 Boston, MA 02111 (US)
Inventors: BACHOVCHIN, William, W.; (US).
LAI, Hung-Sen; (US).
WU, Wengen; (US)
Agent: GORDON, Dana, M.; (US).
BLOUNT, Jennifer, V.; (US).
AKHIEZER, Alexander; (US).
ABELLEIRA, Susan, M.; (US).
CAI, Mi; (US)
Priority Data:
62/482,750 07.04.2017 US
62/384,403 07.09.2016 US
62/384,407 07.09.2016 US
Title (EN) COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PD-1 ANTAGONISTS
(FR) POLYTHÉRAPIES UTILISANT DES INHIBITEURS IMMUNO-DASH ET DES ANTAGONISTES DE PD-1
Abstract: front page image
(EN)Disclosed are combination therapies including administration of I-DASH inhibitors, a PGE2 antagonist and PD-1 pathway inhibitor, and the use of such therapies in the treatment of cell proliferative diseases.
(FR)L'invention concerne des polythérapies comprenant l'administration d'inhibiteurs I-DASH, d'un antagoniste de PGE2 et d'un inhibiteur de la voie PD-1, et l'utilisation de telles thérapies dans le traitement de maladies prolifératives cellulaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)