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1. (WO2018049008) DASH INHIBITORS, AND USES RELATED THERETO
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Pub. No.: WO/2018/049008 International Application No.: PCT/US2017/050445
Publication Date: 15.03.2018 International Filing Date: 07.09.2017
IPC:
A61K 31/69 (2006.01) ,C07D 207/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
69
Boron compounds
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
207
Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
04
having no double bonds between ring members or between ring members and non-ring members
10
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
16
Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applicants:
TRUSTEES OF TUFTS COLLEGE [US/US]; Office of Technology and Industry Collaboration 136 Harrison Avenue, 75K-401 Boston, MA 02111, US
Inventors:
BACHOVCHIN, William, W.; US
LAI, Hung-sen; US
WU, Wengen; US
Agent:
GORDON, Dana, M.; US
BLOUNT, Jennifer, V.; US
AKHIEZER, Alexander; US
ABELLEIRA, Susan, M; US
CAI, Mi; US
Priority Data:
62/384,40307.09.2016US
62/384,40707.09.2016US
62/482,75007.04.2017US
Title (EN) DASH INHIBITORS, AND USES RELATED THERETO
(FR) INHIBITEURS DE DASH, ET UTILISATIONS ASSOCIÉES
Abstract:
(EN) Disclosed are potent immuno-DASH inhibitors and their use in the treatment of cell proliferative diseases.
(FR) L'invention concerne de puissants inhibiteurs de DASH immunitaire et leur utilisation dans le traitement de maladies à prolifération cellulaire.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)