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1. (WO2018048973) BIOSYNTHETIC HEPARIN
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/048973 International Application No.: PCT/US2017/050385
Publication Date: 15.03.2018 International Filing Date: 07.09.2017
IPC:
C12N 9/10 (2006.01) ,C12P 19/04 (2006.01) ,C12P 19/64 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
04
Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
64
Preparation of S-glycosides, e.g. lincomycin
Applicants: RENSSELAER POLYTECHNIC INSTITUTE[US/US]; 110 8th Street Troy, New York 12180-3590, US
Inventors: DOUAISI, Marc; US
GROVER, Navdeep; US
DATTA, Payel; US
PASKALEVA, Elena; US
LIN, Lei; US
BRODFUEHRER, Paul; US
SIMMONS, Trevor J.; US
ONISHI, Akihiro; US
HIRAKANE, Makoto; US
FU, Li; US
LI, Kevin; US
LINHARDT, Robert J.; US
DORDICK, Jonathan; US
MORI, Daisuke; US
Agent: MAEBIUS, Stephen; US
AGARWAL, Pavan K.; US
BECK, George; US
BERKOWITZ, Benjamin; US
BRINCKERHOFF, Courtenay; US
FELDHAUS, John J.; US
KAMINSKI, Michael D.; US
LAW, Glenn; US
QUILLIN, George E.; US
RAWLINS, Andrew E.; US
SCHORR, Kristel; US
SIMKIN, Michele; US
Priority Data:
62/384,34107.09.2016US
Title (EN) BIOSYNTHETIC HEPARIN
(FR) HÉPARINE BIOSYNTHÉTIQUE
Abstract:
(EN) The present disclosure relates to synthesis of heparin, which may be bioequivalent to porcine USP Heparin Sodium. The synthesis may involve three intermediates starting from heparosan.
(FR) L'invention concerne la synthèse d'héparine pouvant être bioéquivalente à l'héparine sodique USP porcine. La synthèse peut impliquer trois intermédiaires, à commencer par l'héparosane.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)