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1. (WO2018048318) CAMEL DERIVED POLYPEPTIDES BINDING HUMAN CD3, IDENTIFIED USING A NOVEL ONE-STEP METHOD
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/048318    International Application No.:    PCT/QA2017/050004
Publication Date: 15.03.2018 International Filing Date: 07.09.2017
IPC:
Applicants: ANTI-DOPING LAB QATAR [QA/QA]; Sports City Road P.O. Box 27775 Doha (QA)
Inventors: VITO, Pasquale; (QA).
MOHAMED-ALI, Vidya; (QA).
ALSAYRAFI, Mohammed; (QA)
Agent: HALLAK, Alexios; (QA)
Priority Data:
QA/201609/00402 07.09.2016 QA
Title (EN) CAMEL DERIVED POLYPEPTIDES BINDING HUMAN CD3, IDENTIFIED USING A NOVEL ONE-STEP METHOD
(FR) POLYPEPTIDES DÉRIVÉS DU CHAMEAU SE LIANT AU CD3 HUMAIN, IDENTIFIÉS À L'AIDE D'UNE NOUVELLE MÉTHODE EN UNE ÉTAPE
Abstract: front page image
(EN)The present invention relates to variable domains of camelid heavy-chain antibodies (VHH domains) directed against the human CD3ε component of the T cell receptor and specifically to methods of use of said polypeptides for delivering prophylactic, therapeutic or diagnostic compounds to human T lymphocytes. It further describes a novel one-step method for the identification of phage displayed camel monoclonal antibodies.
(FR)La présente invention concerne des domaines variables d'anticorps à chaîne lourde de camélidés (domaines VHH) dirigés contre l'élément CD3ε humain du récepteur de lymphocytes T et, plus précisément, des méthodes d'utilisation desdits polypeptides pour l'apport de composés prophylactiques, thérapeutiques ou diagnostiques à des lymphocytes T humains. L'invention concerne en outre une nouvelle méthode en une étape pour l'identification d'anticorps monoclonaux de chameau exposés sur phage.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)