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1. (WO2018048317) MONOCLONAL ANTIBODIES AGAINST HEMAGGLUTININ OF H5-SEROTYPE INFLUENZA VIRUSES AND THEIR USES, HYBRIDOMAS PRODUCING SAID ANTIBODIES, COMPOSITIONS AND DIAGNOSTIC KITS
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Pub. No.: WO/2018/048317 International Application No.: PCT/PL2017/000084
Publication Date: 15.03.2018 International Filing Date: 11.09.2017
Chapter 2 Demand Filed: 11.07.2018
IPC:
C07K 16/10 (2006.01) ,A61K 39/42 (2006.01) ,G01N 33/569 (2006.01) ,G01N 33/577 (2006.01) ,C12N 7/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08
against material from viruses
10
from RNA viruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
42
viral
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
577
involving monoclonal antibodies
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7
Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
Applicants:
INSTYTUT BIOTECHNOLOGII I ANTYBIOTYKÓW [PL/PL]; ul. Starościńska 5 PL-02-516 Warszawa, PL
KRZYSZTOF KUCHARCZYK TECHNIKI ELEKTROFORETYCZNE SP. Z O.O. [PL/PL]; ul. Dzieci Warszawy 31/20 PL-02-495 Warszawa, PL
UNIWERSYTET GDAŃSKI [PL/PL]; ul. Bażyńskiego 8 PL-80-309 Gdańsk, PL
Inventors:
SĄCZYŃSKA, Violetta; PL
CECUDA-ADAMCZEWSKA, Violetta; PL
PORĘBSKA, Anna; PL
FLORYS, Katarzyna; PL
BIERCZYŃSKA-KRZYSIK, Anna; PL
BARAN, Piotr; PL
ROMANIK-CHRUŚCIELEWSKA, Agnieszka; PL
PŁUCIENNICZAK, Grażyna; PL
PŁUCIENNICZAK, Andrzej; PL
BOROWICZ Piotr; PL
KUCHARCZYK, Krzysztof; PL
SZEWCZYK, Bogusław; PL
Agent:
ROŻKOWICZ, Anna; WTS Rzecznicy Patentowi Witek, Śnieżko & Partners ul. Weigla 12 PL-53-114 Wrocław, PL
Priority Data:
P.418 67112.09.2016PL
Title (EN) MONOCLONAL ANTIBODIES AGAINST HEMAGGLUTININ OF H5-SEROTYPE INFLUENZA VIRUSES AND THEIR USES, HYBRIDOMAS PRODUCING SAID ANTIBODIES, COMPOSITIONS AND DIAGNOSTIC KITS
(FR) ANTICORPS MONOCLONAUX CONTRE L'HÉMAGGLUTININE DES VIRUS DE LA GRIPPE DE SÉROTYPE H5 ET LEURS UTILISATIONS, HYBRIDOMES PRODUISANT LESDITS ANTICORPS, COMPOSITIONS ET KITS DE DIAGNOSTIC
Abstract:
(EN) The object of the invention are monoclonal antibodies against hemagglutinin of H5-serotype influenza viruses selected from the group comprising G-1-31-22, G-2-14-10, G-5-32-5, G-6-42-42, G-7-24-17 and G-7-27-18, having a broad application in immunoprophyiaxis and immunotherapy of infections evoked by H5-serotype influenza viruses in humans and animals. The invention also provides hybridomas producing said antibodies, as well as compositions and diagnostic kits containing said antibodies for the detection and typing of H5-serotype influenza viruses and antibodies against H5-serotype influenza viruses in biological samples.
(FR) L'objet de l'invention concerne des anticorps monoclonaux contre l'hémagglutinine des virus de la grippe de sérotype H5 sélectionnés dans le groupe comprenant G-1-31-22, G-2-14-10, G-5-32-5, G-6-42-42, G-7-24-17 et G-7-27-18, ayant une large application dans immunoprophylaxie et l'immunothérapie d'infections provoquées par des virus de la grippe de sérotype H5 chez l'homme et l'animal. L'invention concerne également des hybridomes produisant lesdits anticorps, ainsi que des compositions et des kits de diagnostic contenant lesdits anticorps pour la détection et le typage des virus de la grippe de sérotype H5 et des anticorps contre les virus de la grippe de sérotype H5 dans des échantillons biologiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)