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1. (WO2018048296) ANTIFUNGAL COMPOSITION DERIVED FROM CLITORIA TERNATEA FLAVONOID

Pub. No.:    WO/2018/048296    International Application No.:    PCT/MY2017/050047
Publication Date: Fri Mar 16 00:59:59 CET 2018 International Filing Date: Sat Aug 12 01:59:59 CEST 2017
IPC: A61K 31/353
A61P 31/10
Applicants: UNIVERSITI SAINS MALAYSIA
Inventors: MANSOR, Sharif Mahsufi
RAMANATHAN, Surash
MURUGAIAH, Vickneswaran
LINGGAM, Kamilla
Title: ANTIFUNGAL COMPOSITION DERIVED FROM CLITORIA TERNATEA FLAVONOID
Abstract:
The present invention relates to antifungal compositions derived from Clitoria ternatea. More particularly, the present invention relates to a flavonoid composition for use as an antifungal agent, characterized in that, the composition comprises kaempferol-3-O- a-rhamnopyranosyl-(1-2)-β-10 glucopyranoside, method of manufacturing and method of use thereof. Furthermore the present invention provides a novel approach for development of a flavonoid composition comprising kaempferol-3-O-a-rhamnopyranosyl- (1-2)-β-glucopyranoside that can be combined with other drugs to form a synergistic drug combination that is capable of inhibiting fungal growth at low concentration effectively.