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1. (WO2018047143) VISTA SIGNALING PATHWAY INHIBITORY COMPOUNDS USEFUL AS IMMUNOMODULATORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/047143 International Application No.: PCT/IB2017/055488
Publication Date: 15.03.2018 International Filing Date: 12.09.2017
IPC:
C07D 291/00 (2006.01) ,A61K 31/00 (2006.01)
Applicants: AURIGENE DISCOVERY TECHNOLOGIES LIMITED[IN/IN]; 39-40, KIADB Industrial Area, Electronic City Phase II, Hosur Road, Karnataka Bangalore 560100, IN
Inventors: SASIKUMAR, Pottayil Govindan Nair; IN
RAMACHANDRA, Muralidhara; IN
NAREMADDEPALLI, Seetharamaiah Setty Sudarshan; IN
Priority Data:
20164103112912.09.2016IN
Title (EN) VISTA SIGNALING PATHWAY INHIBITORY COMPOUNDS USEFUL AS IMMUNOMODULATORS
(FR) COMPOSÉS INHIBITEURS DE LA VOIE DE SIGNALISATION VISTA UTILES EN TANT QU'IMMUNOMODULATEURS
Abstract:
(EN) The present invention relates to VISTA signaling pathway inhibitory compounds of formula (I) which are useful as immune modulators for the treatment of various disease conditions including various types of cancer. The invention also encompasses the use of the compound of formula (I) and pharmaceutically acceptable salts thereof for the treatment of diseases or disorders mediated by VISTA.
(FR) La présente invention concerne des composés inhibiteurs de la voie de signalisation VISTA de formule (I) qui sont utiles en tant que modulateurs immunitaires pour le traitement de divers états pathologiques comprenant divers types de cancer. L'invention concerne également l'utilisation du composé de formule (I) et de sels pharmaceutiquement acceptables de celui-ci pour le traitement de maladies ou de troubles induites par VISTA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)