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1. (WO2018047080) METHODS FOR PURIFYING ANTIBODIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/047080    International Application No.:    PCT/IB2017/055374
Publication Date: 15.03.2018 International Filing Date: 06.09.2017
IPC:
C07K 1/22 (2006.01)
Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED [GB/GB]; 980 Great West Road Brentford Middlesex TW89GS (GB)
Inventors: DUMETZ, Andre C.; (US).
GOKLEN, Kent E.; (US).
LEVY, Nicholas E.; (US).
MOLEK, Jessica Rachel; (US).
THOMSON, Andrew S.; (US).
YANCEY, Kenneth G.; (US)
Priority Data:
62/384,240 07.09.2016 US
Title (EN) METHODS FOR PURIFYING ANTIBODIES
(FR) PROCÉDÉS DE PURIFICATION D'ANTICORPS
Abstract: front page image
(EN)The present invention relates to a method of purifying a recombinant polypeptide from Host Cell Proteins (HCP), the method comprising: (a) applying a solution comprising the recombinant polypeptide and HCP to a superantigen chromatography solid support, (b) washing the superantigen chromatography solid support with a wash buffer comprising caprylate and arginine; and (c) eluting the recombinant polypeptide from the superantigen chromatography solid support.
(FR)L'invention concerne un procédé de purification d'un polypeptide recombiné de protéines de cellules hôtes (HCP), ce procédé consistant : (a) à appliquer une solution contenant le polypeptide recombiné et les HCP sur un support solide de chromatographie de superantigènes; (b) à laver le support solide de chromatographie de superantigènes avec un tampon de lavage contenant du caprylate et de l'arginine; et (c) à éluer le polypeptide recombiné du support solide de chromatographie sur superantigènes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)