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1. (WO2018046662) [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/046662    International Application No.:    PCT/EP2017/072582
Publication Date: 15.03.2018 International Filing Date: 08.09.2017
IPC:
C07B 59/00 (2006.01)
Applicants: UNIVERSITÉ CATHOLIQUE DE LOUVAIN [BE/BE]; Place de l'Université 1 1348 Louvain-la-Neuve (BE)
Inventors: SONVEAUX, Pierre; (BE).
LABAR, Daniel; (BE).
VAN HÉE, Vincent; (BE).
DEHON, Gwenaël; (BE).
FRÉDÉRICK, Raphaël; (BE)
Agent: ICOSA; 83 avenue Denfert-Rochereau 75014 Paris (FR)
Priority Data:
16188093.5 09.09.2016 EP
Title (EN) [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER
(FR) DÉRIVÉ DE LACTATE MARQUÉ [ 18 F] EN TANT QUE RADIOTRACEUR TEP
Abstract: front page image
(EN)The present invention relates to a positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is a [18F] -labelled lactate derivative. The invention also provides a process for the radiosynthesis of the [18F]-labelied lactate derivative. The invention further relates to the use of the [18F]-iabelied lactate derivative for imaging lactate uptake in living cells, especially in humans.
(FR)La présente invention concerne un radiotraceur de tomographie par émission de positrons (TEP) pour l'imagerie de l'absorption de lactate, le traceur étant un dérivé de lactate marqué [ 18 F]. L'invention concerne également un procédé de radio-synthèse du dérivé de lactate marqué [ 18 F]. L'invention concerne en outre l'utilisation du dérivé de lactate marqué [ 18 F] pour l'imagerie de l'absorption de lactate dans des cellules vivantes, en particulier chez l'être humain.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)