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1. (WO2018046485) USE OF BUTYRICIMONAS AND/OR OXALOBACTER FOR TREATING IRRITABLE BOWEL SYNDROME
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Pub. No.: WO/2018/046485 International Application No.: PCT/EP2017/072207
Publication Date: 15.03.2018 International Filing Date: 05.09.2017
IPC:
A61K 35/74 (2015.01) ,A61P 1/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
Applicants: SWECURE AB[SE/SE]; Stureplan 15 SE-111 45 Stockholm, SE
Inventors: SIMRÉN, Magnus; SE
WOLD, Agnes; SE
ADLERBERTH, Ingegerd; SE
SJÖBERG, Fei; SE
Agent: STRÖM & GULLIKSSON AB; P.O. Box 4188 SE-203 13 MALMÖ, SE
Priority Data:
1651214-709.09.2016SE
Title (EN) USE OF BUTYRICIMONAS AND/OR OXALOBACTER FOR TREATING IRRITABLE BOWEL SYNDROME
(FR) UTILISATION DE BUTYRICIMONAS ET/OU D'OXALOBACTER POUR TRAITER LE SYNDROME DE L'INTESTIN IRRITABLE
Abstract:
(EN) The application discloses a composition comprising a therapeutically effective amount of any species of viable Butyricimonas and/or Oxalobacter bacteria and a carrier or excipient for use in the prevention or treatment of irritable bowel disease (IBS) in a subject. The application further discloses a method of treating or reducing a severity of at least one symptom of the gastrointestinal disease irritable bowel syndrome (IBS), comprising administering to a human subject a composition comprising bacterial strains of genus Butyricimonas and/or Oxalobacter in an amount effective to populate a gastrointestinal tract in the subject, thereby providing an amount effective to treat the gastrointestinal disease or reduce a severity of at least one symptom of the gastrointestinal disease in the subject.
(FR) L'invention concerne une composition comprenant une quantité thérapeutiquement efficace de bactéries viables d'espèces quelconques des genres Butyricimonas et/ou Oxalobacter ainsi qu'un support ou excipient, destinée à être utilisée chez le patient dans la prévention ou le traitement du syndrome de l'intestin irritable (SII). L'invention concerne en outre une méthode permettant de traiter au moins un symptôme d'une maladie gastro-intestinale, le syndrome de l'intestin irritable (SII), ou de diminuer la gravité de ce symptôme, la méthode comprenant l'administration à un patient humain d'une composition comprenant des souches bactériennes des genres Butyricimonas et/ou Oxalobacter en une quantité suffisante pour coloniser le tractus gastro-intestinal du patient, apportant ainsi une quantité efficace pour traiter la maladie gastro-intestinale ou diminuer la gravité d'au moins un symptôme de la maladie gastro-intestinale chez le patient.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)