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1. (WO2018045371) nNIF AND nNIF-RELATED PEPTIDES AND RELATED METHODS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2018/045371 International Application No.: PCT/US2017/050072
Publication Date: 08.03.2018 International Filing Date: 05.09.2017
IPC:
A61K 38/00 (2006.01) ,A61K 38/57 (2006.01) ,A61K 47/48 (2006.01) ,A61K 47/60 (2017.01) ,C07K 14/47 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
57
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
[IPC code unknown for A61K 47/60]
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants:
THE UNIVERSITY OF UTAH RESEARCH FOUNDATION [US/US]; 615 Arapeen Drive Suite 310 Salt Lake City, Utah 84108, US
Inventors:
YOST, Christian Con; US
ZIMMERMAN, Guy A.; US
WEYRICH, Andrew S.; US
SCHIFFMAN, Joshua; US
Agent:
GIDDINGS, Barton W.; US
Priority Data:
62/383,24302.09.2016US
62/492,01928.04.2017US
Title (EN) nNIF AND nNIF-RELATED PEPTIDES AND RELATED METHODS
(FR) NNIF ET PEPTIDES APPARENTÉS À NNIF ET MÉTHODES ASSOCIÉES
Abstract:
(EN) Neonatal NET-Inhibitory Factor (nNIF) and nNIF-Related Peptides (NRPs) are provided. Methods for the treatment of and prophylaxis against inflammatory disorders and cancer are also provided. Additionally, methods for the inhibition of metastasis in patients having cancer are provided. The methods can include administering nNIF and/or a NRP to patients having, or at risk of developing, an inflammatory disorder or a cancer.
(FR) L'invention concerne un facteur inhibiteur de NET néonatal (nNIF) et des peptides apparentés à nNIF (NRP). L'invention concerne également des méthodes de traitement et de prophylaxie des troubles inflammatoires et du cancer. De plus, l'invention concerne des méthodes d'inhibition des métastases chez des patients atteints d'un cancer. Les méthodes peuvent consister à administrer le nNIF et/ou un NRP à des patients atteints d'un trouble inflammatoire ou d'un cancer, ou présentant un risque de développer un trouble inflammatoire ou un cancer.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)