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1. (WO2018045267) METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING ANTIRETROVIRAL TREATMENT
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Pub. No.: WO/2018/045267 International Application No.: PCT/US2017/049817
Publication Date: 08.03.2018 International Filing Date: 01.09.2017
IPC:
A61K 39/12 (2006.01) ,A61P 31/18 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
14
for RNA viruses
18
for HIV
Applicants:
JANSSEN VACCINES & PREVENTION B.V. [NL/NL]; Archimedesweg 4-6 2333 CN Leiden, NL
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. [US/US]; 330 Brookline Avenue Boston, MA 02215, US
HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. [US/US]; 6720A Rockledge Drive Suite 100 Bethesda, MD 20817, US
WALTER REED ARMY INSTITUTE OF RESEARCH [US/US]; 503 Robert Grant Avenue Silver Spring, MD 20910, US
Inventors:
TOMAKA, Frank; US
PAU, Maria, Grazia; NL
SCHUITEMAKER, Johanna; NL
BAROUCH, Dan; US
ANANWORANICH, Jintanat; US
ROBB, Merlin; US
MICHAEL, Nelson, L.; US
KIM, Jerome; US
Agent:
SHANAHAN, Carly, A.; US
BELISARIO, Martin, G.; US
ELIAS, Ragi, A.i; US
BARANIAK, Andrew, P.; US
BUTLER, Dennis, J.; US
Priority Data:
62/383,14002.09.2016US
Title (EN) METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING ANTIRETROVIRAL TREATMENT
(FR) PROCÉDÉS POUR INDUIRE UNE RÉPONSE IMMUNITAIRE CONTRE UNE INFECTION PAR LE VIRUS DE L'IMMUNODÉFICIENCE HUMAINE CHEZ DES SUJETS SUBISSANT UN TRAITEMENT ANTIRÉTROVIRAL
Abstract:
(EN) Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens.
(FR) L'invention concerne des procédés pour induire une réponse immunitaire contre le Virus de l'immunodéficience humaine (VIH) chez des sujets infectés par le VIH et subissant une thérapie antirétrovirale (ART). Les procédés comprennent l'administration d'un vaccin d'amorce de vecteur d'adénovirus et d'un vaccin de rappel de vecteur de virus de la vaccine modifié (MVA) codant pour des antigènes du VIH en mosaïque.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)