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1. (WO2018045258) TREATMENT OF TNF-alpha CYTOTOXICITY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/045258    International Application No.:    PCT/US2017/049802
Publication Date: 08.03.2018 International Filing Date: 01.09.2017
IPC:
C12Q 1/68 (2006.01), G01N 33/50 (2006.01), G01N 33/569 (2006.01), G01N 33/574 (2006.01)
Applicants: THE UNIVERSITY OF CHICAGO [US/US]; 5801 S. Ellis Avenue Chicago, Illinois 60208 (US)
Inventors: LIN, Anning; (US)
Agent: ISENBARGER, Thomas A.; (US)
Priority Data:
62/382,829 02.09.2016 US
Title (EN) TREATMENT OF TNF-alpha CYTOTOXICITY
(FR) TRAITEMENT DE CYTOTOXICITÉ DU TNF-ALPHA
Abstract: front page image
(EN)Provided herein is technology relating to treating and/or ameliorating TNFα cytotoxicity and particularly, but not exclusively, to compositions, methods, and kits for specifically modulating BCL-2-associated death promoter (BAD) activity, for example, by modulating the activity of Src and/or p190GAP.
(FR)L'invention concerne une technologie se rapportant au traitement et/ou à l'amélioration de la cytotoxicité du TNFα et, en particulier, mais pas exclusivement, des compositions, des procédés, et des kits pour moduler spécifiquement l'activité du promoteur de mort associé à BCL-2 (BAD), par exemple, par modulation de l'activité de Src et/ou p190GAP.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)