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1. (WO2018045091) OPHTHALMIC COMPOSITIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/045091    International Application No.:    PCT/US2017/049473
Publication Date: 08.03.2018 International Filing Date: 30.08.2017
IPC:
A61K 31/00 (2006.01)
Applicants: AERIE PHARMACEUTICALS, INC. [US/US]; 135 US Highway 206, Suite 15 Bedminster, NJ 07921 (US)
Inventors: LIN, Cheng-Wen; (US).
KOPCZYNSKI, Casey; (US).
DELONG, Mitchell, A.; (US).
STURDIVANT, Jill, M.; (US).
KRISHNAMOORTHY, Ramesh; (US)
Agent: CULLMAN, Louis C.; (US).
NOVAK, B.j.; (US).
CULLMAN, Louis, C.; (US).
KEFALLINOS, G.; (US).
GLASKY BERGMAN, M.; (US)
Priority Data:
62/382,237 31.08.2016 US
Title (EN) OPHTHALMIC COMPOSITIONS
(FR) COMPOSITIONS OPHTALMIQUES
Abstract: front page image
(EN)The present disclosure provides an ophthalmic composition comprising 4-(3-amino-1-(isoquinoiin-6-yiamino)-1-oxopropan-2-yi)benzyi 2,4-dirnethylbenzoate or its pharmaceutically acceptable salts; about 0.01% weight/volume to about 1.0% weight/volume of a buffer; and about 0.01% weight/volume to about 10% weight/volume of a tonicity agent.
(FR)La présente invention concerne une composition ophtalmique comprenant de la 4-(3-amino-1-(isoquinoiin-6-yiamino)-1-oxopropan-2-yi)benzyi 2,4-dirnethylbenzoate ou de ses sels pharmaceutiquement acceptables; d'environ 0,01% en poids/volume à environ 1,0% en poids/volume d'un tampon; et environ 0,01% en poids/volume à environ 10% en poids/volume d'un agent de tonicité.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)