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1. (WO2018045091) OPHTHALMIC COMPOSITIONS

Pub. No.:    WO/2018/045091    International Application No.:    PCT/US2017/049473
Publication Date: Fri Mar 09 00:59:59 CET 2018 International Filing Date: Thu Aug 31 01:59:59 CEST 2017
IPC: A61K 31/00
Applicants: AERIE PHARMACEUTICALS, INC.
Inventors: LIN, Cheng-Wen
KOPCZYNSKI, Casey
DELONG, Mitchell, A.
STURDIVANT, Jill, M.
KRISHNAMOORTHY, Ramesh
Title: OPHTHALMIC COMPOSITIONS
Abstract:
The present disclosure provides an ophthalmic composition comprising 4-(3-amino-1-(isoquinoiin-6-yiamino)-1-oxopropan-2-yi)benzyi 2,4-dirnethylbenzoate or its pharmaceutically acceptable salts; about 0.01% weight/volume to about 1.0% weight/volume of a buffer; and about 0.01% weight/volume to about 10% weight/volume of a tonicity agent.