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1. (WO2018045054) HIGHLY CONCENTRATED LOW VISCOSITY MASP-2 INHIBITORY ANTIBODY FORMULATIONS, KITS, AND METHODS

Pub. No.:    WO/2018/045054    International Application No.:    PCT/US2017/049415
Publication Date: Fri Mar 09 00:59:59 CET 2018 International Filing Date: Thu Aug 31 01:59:59 CEST 2017
IPC: A61K 9/08
A61K 39/395
A61K 47/00
Applicants: OMEROS CORPORATION
Inventors: DEMOPULOS, Gregory, A.
FERGUSON, Kenneth, M.
LAMBERT, William, Joseph
WHITAKER, John, Steven
Title: HIGHLY CONCENTRATED LOW VISCOSITY MASP-2 INHIBITORY ANTIBODY FORMULATIONS, KITS, AND METHODS
Abstract:
The present invention relates to stable, high-concentration low-viscosity formulations of MASP-2 inhibitory antibodies, kits comprising the formulations and therapeutic methods using the formulations and kits for inhibiting the adverse effects of MASP-2 dependent complement activation.