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1. (WO2018045015) METHODS AND KITS FOR REDUCING THE SUSCEPTIBILITY OF LIPOPROTEIN PARTICLES TO ATHEROGENIC AGGREGATION INDUCED BY ARTERIAL-WALL ENZYMES
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Pub. No.: WO/2018/045015 International Application No.: PCT/US2017/049351
Publication Date: 08.03.2018 International Filing Date: 30.08.2017
IPC:
A61K 47/24 (2006.01) ,A61K 8/55 (2006.01) ,A61K 9/127 (2006.01) ,G01N 33/50 (2006.01) ,G01N 33/92 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
24
containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen or sulfur
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
55
containing phosphorus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
92
involving lipids, e.g. cholesterol
Applicants:
WILLIAMS, Kevin, Jon [US/US]; US
Inventors:
WILLIAMS, Kevin, Jon; US
Agent:
FRIED, Allan, H.; US
Priority Data:
62/382,36801.09.2016US
Title (EN) METHODS AND KITS FOR REDUCING THE SUSCEPTIBILITY OF LIPOPROTEIN PARTICLES TO ATHEROGENIC AGGREGATION INDUCED BY ARTERIAL-WALL ENZYMES
(FR) PROCÉDÉS ET KITS POUR RÉDUIRE LA TENDANCE DE PARTICULES DE LIPOPROTÉINE À L'AGRÉGATION ATHÉROGÈNE INDUITE PAR DES ENZYMES DE PAROI ARTÉRIELLE
Abstract:
(EN) Methods of decreasing, in a human or other animal, the susceptibility of atherogenic particles to aggregation induced by sphingomyelinase, the methods comprising administering vesicles to the animal. Also similar methods directed at the formation of cholesterol crystals, abnormal cholesterol enrichment of cell membranes, and denaturation of Apo B.
(FR) L'invention concerne des procédés pour réduire, chez un être humain ou un autre animal, la tendance de particules athérogènes à l'agrégation induite par la sphingomyélinase, ces procédés comprenant l'administration de vésicules à l'animal. L'invention concerne également des procédés similaires dirigés contre la formation de cristaux de cholestérol, l'enrichissement anormal du cholestérol des membranes cellulaires et la dénaturation de l'Apo B.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)