WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018044920) TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/044920    International Application No.:    PCT/US2017/049170
Publication Date: 08.03.2018 International Filing Date: 29.08.2017
IPC:
A61K 47/18 (2017.01), A61K 47/36 (2006.01), A61K 47/42 (2017.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, Twelfth Floor Oakland, CA 94607-5200 (US)
Inventors: ZAKREWSKY, Michael; (US).
MITRAGOTRI, Samir; (US)
Agent: PABST, Patrea, L.; (US).
SHYNTUM, Yvonne, Y.; (US).
RAYMOND, Robert, A.; (US).
MONHEIT, Rivka, D.; (US).
REY, Adam, S.; (US)
Priority Data:
62/380,761 29.08.2016 US
Title (EN) TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT
(FR) FORMULATIONS TOPIQUES A BASE D’ESPÈCES IONIQUES POUR LE TRAITEMENT DE LA PEAU
Abstract: front page image
(EN)Compositions containing a complex that contains a cation with alkyl chains and a macromolecule anion, and methods of making and using are disclosed. The compositions are typically charge neutral and a liquid at room temperature and standard pressure. The macromolecule anions may be nucleic acids, peptides, proteins, and/or carbohydrates. The compositions have enhanced penetration across the skin barrier (stratum corneum) and into the skin cells, delivering the macromolecules to the skin cells. The compositions are topically applied to the skin and are particularly useful for treatment of skin conditions.
(FR)L'invention concerne des compositions contenant un complexe qui contient un cation avec des chaînes alkyle et un anion macromolécule, et des procédés de fabrication et d'utilisation. Les compositions sont typiquement neutres et un liquide à température ambiante et pression standard. Les anions macromolécules peuvent être des acides nucléiques, des peptides, des protéines et/ou des glucides. Les compositions ont une pénétration améliorée à travers la barrière cutanée (couche cornée) et dans les cellules cutanées, délivrant les macromolécules aux cellules cutanées. Les compositions sont appliquées par voie topique sur la peau et sont particulièrement utiles pour le traitement d'affections cutanées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)