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1. (WO2018044724) TREATMENT OF DISEASE WITH N-ACETYL KYNURENINE
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Pub. No.: WO/2018/044724 International Application No.: PCT/US2017/048662
Publication Date: 08.03.2018 International Filing Date: 25.08.2017
IPC:
A61K 31/198 (2006.01) ,A61K 39/00 (2006.01)
[IPC code unknown for A61K 31/198][IPC code unknown for A61K 39]
Applicants:
AMPIO PHARMACEUTICALS, INC. [US/US]; 373 Inverness Parkway Suite 200 Englewood, CO 80112, US
Inventors:
BAR-OR, David; US
RAEL, Leonard, T.; US
BAR-OR, Raphael; US
Agent:
DOMITROVICH, Angela, M.; US
Priority Data:
62/381,82431.08.2016US
Title (EN) TREATMENT OF DISEASE WITH N-ACETYL KYNURENINE
(FR) TRAITEMENT D'UNE MALADIE AVEC DE LA N-ACÉTYL-KYNURÉNINE
Abstract:
(EN) The invention provides a method, composition and kit for treating T-cell mediated diseases, degenerative joint diseases or diseases mediated by platelet activating factor (PAF) comprising administering to an animal in need thereof, an effective amount a pharmaceutical composition containing N-acetyl-kynurenine (NAK) or pharmaceutically acceptable salts thereof as the active ingredient.
(FR) L'invention concerne une méthode, une composition et une trousse de traitement de maladies médiées par des lymphocytes T, de maladies articulaires dégénératives ou de maladies médiées par le facteur d'activation plaquettaire (PAF), la méthode consistant à administrer à un animal qui en a besoin une quantité efficace d'une composition pharmaceutique contenant de la N-acétyl-kynurénine (NAK) ou des sels pharmaceutiquement acceptables de celle-ci comme principe actif.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)