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1. WO2018044020 - METHOD FOR PREPARING EPERISONE SUSTAINED RELEASE MICROSPHERE, AND COMPOSITE PREPARATION OF EPERISONE SUSTAINED RELEASE MICROSPHERE AND ACECLOFENAC

Publication Number WO/2018/044020
Publication Date 08.03.2018
International Application No. PCT/KR2017/009394
International Filing Date 29.08.2017
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4453
only substituted in position 1, e.g. propipocaine, diperodon
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
196
the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 9/50 (2006.01)
A61K 9/48 (2006.01)
A61K 9/16 (2006.01)
A61K 9/20 (2006.01)
A61K 31/4453 (2006.01)
A61K 31/196 (2006.01)
CPC
A61K 31/196
A61K 31/4453
A61K 9/16
A61K 9/20
A61K 9/48
A61K 9/50
Applicants
  • 초당약품공업 주식회사 CHO DANG PHARM. CO., LTD. [KR/KR]; 서울시 구로구 공원로8길 24 24, Gongwon-ro 8-gil Guro-gu Seoul 08296, KR
Inventors
  • 이준용 LEE, Joon Yong; KR
Agents
  • 김동완 KIM, Dong Wan; KR
Priority Data
10-2016-010974929.08.2016KR
10-2016-010975229.08.2016KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) METHOD FOR PREPARING EPERISONE SUSTAINED RELEASE MICROSPHERE, AND COMPOSITE PREPARATION OF EPERISONE SUSTAINED RELEASE MICROSPHERE AND ACECLOFENAC
(FR) PROCÉDÉ DE PRÉPARATION DE MICROSPHÈRE À LIBÉRATION PROLONGÉE D’ÉPÉRISONE, ET PRÉPARATION COMPOSITE DE MICROSPHÈRE À LIBÉRATION PROLONGÉE D’ÉPÉRISONE ET D’ACÉCLOFÉNAC
(KO) 에페리손 서방성 미립구의 제조방법 및 에페리손 서방성 미립구와 아세클로페낙 복합제제
Abstract
(EN)
The present invention relates to a method for preparing an eperisone sustained release microsphere, and a composite preparation of a eperisone sustained release microsphere and aceclofenac and, more specifically, to: a method for preparing an eperisone sustained release microsphere, the method using, as a microsphere seed, one or more sugars selected from microcrystalline cellulose, anhydrous lactose, starch, sugar, maltitol, or mannitol, and coating eperisone, an acidifying agent, and a release control polymer; and a composite preparation of an eperisone sustained release microsphere and aceclofenac.
(FR)
La présente invention concerne un procédé de préparation d’une microsphère à libération prolongée d’épérisone, et une préparation composite d’une microsphère à libération prolongée d’épérisone et d’acéclofénac et, plus spécifiquement : un procédé de préparation d’une microsphère à libération prolongée d’épérisone, le procédé utilisant, en tant que germe de microsphère, un ou plusieurs sucres choisis parmi la cellulose microcristalline, le lactose anhydre, l’amidon, un sucre, le maltitol ou le mannitol, et l’enrobage d’épérisone, un agent acidifiant, et un polymère de contrôle de libération ; et une préparation composite d’une microsphère à libération prolongée d’épérisone et d’acéclofénac.
(KO)
본 발명은 에페리손 서방성 미립구의 제조방법 및 에페리손 서방성 미립구와 아세클로페낙 복합제제에 관한 것이다. 더욱 상세하게는 미립구 시드로서 미결정 셀룰로오스, 무수 유당, 전분, 설탕, 말티톨 또는 만니톨에서 선택된 1종 이상의 당을 사용하고 에페리손, 산성화제 및 방출제어 고분자를 코팅시킨 에페리손 서방성 미립구의 제조방법 및 상기 에페리손 서방성 미립구와 아세클로페낙 복합제제에 관한 것이다.
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