WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018043850) PHARMACEUTICAL FORMULATION OF D-CYCLOSERINE AND METHOD FOR PRODUCING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/043850    International Application No.:    PCT/KR2017/002011
Publication Date: 08.03.2018 International Filing Date: 23.02.2017
IPC:
A61K 9/28 (2006.01), A61K 9/00 (2006.01), A61K 31/42 (2006.01)
Applicants: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY [KR/KR]; (Dae-dong) 280, Daehak-ro Gyeongsan-si Gyeongsangbuk-do 38541 (KR)
Inventors: KIM, Jong Oh; (KR).
YONG, Chul Soon; (KR).
CHOI, Han-Gon; (KR).
JIN, Sung Giu; (KR).
YANG, Eun Su; (KR).
KIM, Kyeong Soo; (KR).
KIM, Dong Shik; (KR).
KIM, Jeong Hyeon; (KR).
LEE, Jong Seong; (KR)
Agent: TAEBAEK INTELLECTUAL PROPERTY LAW FIRM; #601 Innoplex 1 cha, 151Gasandigital 1-ro Geumcheon-gu Seoul 08506 (KR)
Priority Data:
10-2016-0113298 02.09.2016 KR
Title (EN) PHARMACEUTICAL FORMULATION OF D-CYCLOSERINE AND METHOD FOR PRODUCING SAME
(FR) FORMULATION PHARMACEUTIQUE DE D-CYCLOSÉRINE ET PROCÉDÉ DE PRODUCTION ASSOCIÉ
(KO) D-싸이클로세린의 약제학적 제형 및 이의 제조방법
Abstract: front page image
(EN)The present invention relates to a pharmaceutical formulation of d-cycloserine and a method for producing same, and can provide an oral preparation of d-cycloserine by producing d-cycloserine by coating, with a Kollicoat® Protect coating material, a mixture comprising d-cycloserine and a pH adjuster selected from magnesium hydroxide and calcium hydroxide, which has improved stability against pH, water and heat, saves the production cost by providing a common, ordinary packaging form without special packaging such as moisture-proof packaging, and shows improved stability by allowing long-term storage and drug activity maintenance.
(FR)La présente invention concerne une formulation pharmaceutique de d-cyclosérine et un procédé de production associé, et permet de fournir une préparation orale de d-cyclosérine, à l'aide d'un procédé de production de d-cyclosérine consistant à enrober avec un matériau de revêtement de Kollicoat ® un mélange comprenant d-cyclosérine et un agent d'équilibrage du pH choisi parmi l'hydroxyde de magnésium et l'hydroxyde de calcium, qui possède une stabilité améliorée par rapport au pH, à l'eau et à la chaleur, permet d'économiser le coût de production en fournissant une forme commune d'emballage ordinaire sans emballage spécial tel qu'un emballage résistant à l'humidité, et démontre une stabilité améliorée en permettant un stockage à long terme et une maintenance d'activité de médicament.
(KO)본 발명은 D-싸이클로세린의 약제학적 제형 및 이의 제조방법에 관한 것으로, D-싸이클로세린 및 수산화마그네슘 또는 수산화칼슘에서 선택된 pH 조절제를 포함하는 혼합물을 Kollicoat® Protect 코팅기제로 코팅하여 D-싸이클로세린을 제조함으로써, pH, 수분 및 열에 대한 안정성을 개선시키고, 방습포장 등의 특수한 포장 없이 통상의 일반적인 포장형태를 제공함으로써 제조비용을 절감시키며, 장기보관 및 약물 활성을 유지시킴으로써 안정성이 개선된 D-싸이클로세린의 경구용 제제를 제공할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)