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1. (WO2018042438) HUMAN BLOOD-DERIVED PRODUCTS HAVING DECREASED FIBRINOLYTIC ACTIVITY AND USES THEREOF IN HEMOSTATIC DISORDERS
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Pub. No.: WO/2018/042438 International Application No.: PCT/IL2017/050977
Publication Date: 08.03.2018 International Filing Date: 31.08.2017
IPC:
A61K 35/14 (2015.01) ,A61K 35/16 (2015.01) ,A61K 38/36 (2006.01) ,A61P 17/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
14
Blood
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
14
Blood
16
Plasma; Serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
36
Blood coagulation or fibrinolysis factors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
02
for treating wounds, ulcers, burns, scars, keloids, or the like
Applicants:
PLAS-FREE LTD [IL/IL]; Wadi El Haj 13 Nazareth, IL
Inventors:
HIJAZI, Abd Alrauf; IL
HIGAZI, Muhamed; IL
Agent:
ZRIHAN-LICHT, Sheila; IL
Priority Data:
62/382,34401.09.2016US
Title (EN) HUMAN BLOOD-DERIVED PRODUCTS HAVING DECREASED FIBRINOLYTIC ACTIVITY AND USES THEREOF IN HEMOSTATIC DISORDERS
(FR) PRODUITS DÉRIVÉS DU SANG HUMAIN À ACTIVITÉ FIBRINOLYTIQUE RÉDUITE ET LEURS UTILISATIONS DANS DES TROUBLES HÉMOSTATIQUES
Abstract:
(EN) The present invention provides therapeutic products with decreased fibrinolytic activity of t-PA-deficient and/or plasminogen-deficient blood products, as well as compositions, kits and methods using the same in treating bleeding associated with hereditary or acquired bleeding disorders. The invention further provides extracorporeal apparatus for blood or blood products Plasmapheresis aimed to prevent or treat bleeding disoreders.
(FR) La présente invention concerne des produits thérapeutiques présentant une activité fibrinolytique réduite préparés à partir de produits sanguins déficients en t-PA et/ou déficients en plasminogène, ainsi que des compositions, des kits et des méthodes les utilisant dans le traitement de saignements associés à des troubles hémorragiques héréditaires ou acquis. L'invention concerne en outre un appareil extracorporel pour plasmaphérèse du sang ou de produits sanguins visant à prévenir ou à traiter des troubles hémorragiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)