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1. (WO2018042367) COMPOUNDS, COMPOSITONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS

Pub. No.:    WO/2018/042367    International Application No.:    PCT/IB2017/055245
Publication Date: Fri Mar 09 00:59:59 CET 2018 International Filing Date: Fri Sep 01 01:59:59 CEST 2017
IPC: C08G 73/02
C08G 63/00
C08G 18/00
Applicants: VYOME BIOSCIENCES PVT. LTD.
Inventors: GHOSH, Sumana
SINHA, Mau
BHATTACHARYYA, Anamika
SADHASIVAM, Suresh
GHOSH, Shamik
SAMANTA, Ritwik
TANDON, Nupur
Title: COMPOUNDS, COMPOSITONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS
Abstract:
The present disclosure is in the field of polymers and pharmaceuticals/antimicrobials. The disclosure provides compounds based on SNAP (synthetic novel antimicrobial polymer) technology, compositions and methods of managing microbial infections including surgical site infections (SSIs). The present compounds are used as a management/therapeutic strategy to target microbial infections and have advantages including excellent antimicrobial potency, biofilm disruption ability, broad spectrum activity against various organisms covering both gram negative and gram positive bacteria as well as fungal pathogens, and low toxicity profile to ensure a healthy therapeutic window for use in humans.