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1. (WO2018041771) (1-METHYLCYCLOPROPYL)METHYL-SUBSTITUTED THIENOURACILES AND USE THEREOF

Pub. No.:    WO/2018/041771    International Application No.:    PCT/EP2017/071531
Publication Date: Fri Mar 09 00:59:59 CET 2018 International Filing Date: Tue Aug 29 01:59:59 CEST 2017
IPC: C07D 495/04
A61K 31/519
A61P 11/08
A61P 35/00
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT
Inventors: HÄRTER, Michael
CANCHO-GRANDE, Yolanda
DELBECK, Martina
KALTHOF, Bernd
LUSTIG, Klemens
Title: (1-METHYLCYCLOPROPYL)METHYL-SUBSTITUTED THIENOURACILES AND USE THEREOF
Abstract:
The invention relates to novel, in position N3, thieno[2,3-d]pyrimidine-2,4-dione ("thienouracil")-derivatives supporting (1-Methylcyclopropyl)methyl-substituents, to methods for the production thereof, to the use thereof alone or in combinations for treating and/or preventing diseases, and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of pulmonary and cardiovascular disorders and cancers.