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1. WO2018041263 - ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE

Publication Number WO/2018/041263
Publication Date 08.03.2018
International Application No. PCT/CN2017/100461
International Filing Date 05.09.2017
IPC
C07D 471/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 403/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
A61P 31/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
16for influenza or rhinoviruses
CPC
A61K 31/4439
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
4439containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61P 31/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
16for influenza or rhinoviruses
C07B 2200/07
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
07Optical isomers
C07D 403/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • 广东众生睿创生物科技有限公司 GUANGDONG RAYNOVENT BIOTECH CO., LTD. [CN]/[CN]
Inventors
  • 熊剑 XIONG, Jian
  • 龙超峰 LONG, Chaofeng
  • 王晶晶 WANG, Jingjing
  • 陈小新 CHEN, Xiaoxin
  • 陈新海 CHEN, KEVIN X
  • 谢程 XIE, Cheng
  • 李鹏 LI, Peng
  • 彭宣嘉 PENG, Xuanjia
  • 黎健 LI, Jian
  • 陈曙辉 CHEN, Shuhui
Agents
  • 上海弼兴律师事务所 SHANGHAI BESHINING LAW OFFICE
Priority Data
201610804101.305.09.2016CN
201611238759.928.12.2016CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE
(FR) DÉRIVÉ DE PYRIMIDINE DU VIRUS DE LA GRIPPE
(ZH) 抗流感病毒嘧啶衍生物
Abstract
(EN) Disclosed are anti-influenza virus compounds, and the use thereof in the preparation of a drug for treating diseases associated with influenza viruses. Specifically disclosed are the compounds as shown in formula (I) and a pharmaceutically acceptable salt thereof.
(FR) L'invention concerne des composés anti-virus de la grippe, et leur utilisation dans la préparation d'un médicament pour le traitement de maladies associées aux virus de la grippe. De façon spécifique, l'invention concerne les composés tel que présenté dans la formule (I) et un sel pharmaceutiquement acceptable de celui-ci.
(ZH) 本发公开了一类抗流感病毒化合物,及其在制备治疗与流感病毒相关药物中的应用。具体公开了式(Ⅰ)所示化合物及其药学上可接受的盐。
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